First experience with sotatercept for pulmonary arterial hypertension in Southern China
20 Aug 2025
byDr. Yiu-Tung Wong, Honorary Consultant in Cardiology, Hong Kong Sanatorium & Hospital; Dr. Ka-Lam Wong, Consultant in Cardiology, Grantham Hospital, Hong Kong; Dr. Bing Lam, Honorary Consultant in Respiratory Medicine, Hong Kong Sanatorium & Hospital, Hong Kong; Dr. Hon-Wah Chan, Honorary Consultant in Cardiology, Hong Kong Sanatorium & Hospital
A 77-year-old male chronic smoker with a history of diabetes
mellitus, hyperÂtension, coronary artery disease treated with stenting to left
circumflex artery and ramus intermediate artery in 2015, chronÂic obstructive
pulmonary disease (COPD), and interstitial lung disease (ILD) presentÂed on 19
January 2024 with shortness of breath (SOB) on exertion, which began following
an episode of COVID-19 in May 2023 and worsened after a subsequent COVID-19
episode in April 2024. Before the two COVID-19 episodes, the patient had good
exercise tolerance and could manage a 1-hour hike.