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Dual RF, ACPA positivity linked to RA manifestations
Patients with rheumatoid arthritis (RA) who are positive for both anticyclic citrullinated peptide antibody (ACPA) and rheumatoid factor (RF) have lower remission rate, higher baseline erythrocyte sedimentation rate (ESR), and need more corticosteroid and disease-modifying antirheumatic drugs (DMARDs) than those with single positivity or double negativity, according to a Singapore study.
Dual RF, ACPA positivity linked to RA manifestations
03 Nov 2025
Empagliflozin 25 mg confers greater kidney protection than SGLT2i 10 mg in T2D
In patients with type 2 diabetes (T2D), empagliflozin 25 mg daily offers greater kidney protection than its 10 mg daily dose or dapagliflozin 10 mg daily, a retrospective cohort study in Hong Kong has shown.
Empagliflozin 25 mg confers greater kidney protection than SGLT2i 10 mg in T2D
03 Nov 2025
Denifanstat reduces lesions in acne vulgaris
The fatty acid synthase inhibitor denifanstat shows potential for treating moderate-to-severe acne vulgaris, with good safety and tolerability, as demonstrated in a study from China presented at EADV 2025.
