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Aspirin protects against pancreatic cancer in people with T2D

15 Jan 2025

For patients with type 2 diabetes (T2D), the use of aspirin appears to lower the risk of incident pancreatic cancer, as shown in a retrospective cohort study.

Aspirin protects against pancreatic cancer in people with T2D

15 Jan 2025

BP target in diabetics: How low should we go?

15 Jan 2025 by

Intensive blood-pressure (BP) lowering treatment targeted at a tighter systolic BP (SBP) yields cardiovascular benefits in Chinese patients with type 2 diabetes (T2D) and elevated BP in the randomized BPROAD* trial.

BP target in diabetics: How low should we go?

15 Jan 2025

[Infographics] ARNI: First-line RASI in 4-pillar GDMT for HFrEF

15 Jan 2025

2024 American College of Cardiology’s Expert Consensus Decision Pathway for Treatment of Heart Failure with Reduced Ejection Fraction (HFrEF), the most recent international guidance on HFrEF treatment, recommends angiotensin receptor/neprilysin inhibitor (ARNI; ie, sacubitril/valsartan) as the preferred renin-angiotensin system inhibitor (RASI), which should be used as first-line therapy whenever possible. Emphasis is placed on initiating and titrating guideline-directed medical therapy (GDMT) early and rapidly. Here is why and how.

[Infographics] ARNI: First-line RASI in 4-pillar GDMT for HFrEF

15 Jan 2025

Potassium binder allows optimized MRA therapy in hyperkalaemic HFrEF patients

15 Jan 2025 by

Treatment with the potassium binder sodium zirconium cyclosilicate (SZC) stabilizes potassium levels in patients with heart failure with reduced ejection fraction (HFrEF) during spironolactone optimization, as shown in the prospective, randomized-withdrawal REALIZE-K trial.

Potassium binder allows optimized MRA therapy in hyperkalaemic HFrEF patients

15 Jan 2025

Sequential oral meds fall short, insulin remains best for gestational diabetes

14 Jan 2025 by

In the management of gestational diabetes, a sequential oral glucose-lowering medication strategy of metformin and additional glyburide, if needed, failed to demonstrate noninferiority to insulin, according to a study.

Sequential oral meds fall short, insulin remains best for gestational diabetes

14 Jan 2025

Resilience tied to better mental health, QoL in bladder cancer

14 Jan 2025

Baseline psychological resources (PR) are associated with improved mental health and quality-of-life (QoL) outcomes over time in patients with bladder cancer, suggest the results of a recent study.

Resilience tied to better mental health, QoL in bladder cancer

14 Jan 2025

Ozanimod delivers real-world clinical benefits in ulcerative colitis

14 Jan 2025 by

Treatment with ozanimod (oza) attains high efficacy rates in real-world clinical practice at week 12 for advanced therapy (AT)-naive patients with moderate-to-severe ulcerative colitis (UC) and at week 26 for those with AT exposure, as shown by initial results from POLARIS, an ongoing phase IV open-label study.

Ozanimod delivers real-world clinical benefits in ulcerative colitis

14 Jan 2025

Testosterone does not induce recurrence in men after RP

14 Jan 2025

Select men who underwent radical prostatectomy (RP) for organ-confined prostate cancer may safely use testosterone therapy, which does not seem to cause biochemical recurrence (BCR), according to a study.

Testosterone does not induce recurrence in men after RP

14 Jan 2025

Acalabrutinib-venetoclax hits mark for fit TN CLL patients

14 Jan 2025 by

The interim analysis of the AMPLIFY trial provides the first phase III evidence of fixed-duration therapy combining a second-generation Bruton tyrosine kinase inhibitor (BTKi) with venetoclax with or without anti-CD20 for treatment-naïve (TN) chronic lymphocytic leukaemia (CLL).

Acalabrutinib-venetoclax hits mark for fit TN CLL patients

14 Jan 2025

Higher daily steps may alleviate depression in adults

14 Jan 2025

Higher daily step count is associated with fewer depressive symptoms in the general adult population, according to the results of a systematic review and meta-analysis.

Higher daily steps may alleviate depression in adults

14 Jan 2025

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Aspirin protects against pancreatic cancer in people with T2D

Aspirin protects against pancreatic cancer in people with T2D

BP target in diabetics: How low should we go?

BP target in diabetics: How low should we go?

[Infographics] ARNI: First-line RASI in 4-pillar GDMT for HFrEF

[Infographics] ARNI: First-line RASI in 4-pillar GDMT for HFrEF

Potassium binder allows optimized MRA therapy in hyperkalaemic HFrEF patients

Potassium binder allows optimized MRA therapy in hyperkalaemic HFrEF patients

Sequential oral meds fall short, insulin remains best for gestational diabetes

Sequential oral meds fall short, insulin remains best for gestational diabetes

Resilience tied to better mental health, QoL in bladder cancer

Resilience tied to better mental health, QoL in bladder cancer

Ozanimod delivers real-world clinical benefits in ulcerative colitis

Ozanimod delivers real-world clinical benefits in ulcerative colitis

Testosterone does not induce recurrence in men after RP

Testosterone does not induce recurrence in men after RP

Acalabrutinib-venetoclax hits mark for fit TN CLL patients

Acalabrutinib-venetoclax hits mark for fit TN CLL patients

Higher daily steps may alleviate depression in adults

Higher daily steps may alleviate depression in adults