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Survival benefits of trastuzumab deruxtecan in patients with previously treated HER2-low mBC

22 May 2025 by

The therapeutic landscape of HER2-low metastatic breast cancer (mBC) has been transformed by the availability of trastuzumab deruxtecan (T-DXd; Enhertu^®, Daiichi Sankyo & AstraZeneca), an antibody-drug conjugate (ADC). At a recent Hong Kong Breast Cancer Foundation (HKBCF) Academic Meeting, Dr Shanu Modi of Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York, US, discussed the efficacy and safety of T-DXd in the phase III DESTINY-Breast04 trial. Local experiences with T-DXd were shared by Dr Roland Leung of the Department of Medicine, the University of Hong Kong.

Survival benefits of trastuzumab deruxtecan in patients with previously treated HER2-low mBC

22 May 2025

Apixaban a safe oral anticoagulant choice for VTE patients

22 May 2025

For patients with venous thromboembolism (VTE) who are initiating an oral anticoagulant, apixaban use appears to be safer than rivaroxaban and warfarin, with lower risks of VTE recurrence and major bleeding, as reported in a study.

Apixaban a safe oral anticoagulant choice for VTE patients

22 May 2025

Mild low birthweight carries increased childhood hypertension risk

21 May 2025 by

Children born with mild low birthweight (LBW) are at increased risk of hypertension, according to new research.

Mild low birthweight carries increased childhood hypertension risk

21 May 2025

UPF categories needed to identify foods linked to cognitive impairment

21 May 2025

Ultraprocessed foods (UPFs) must be separated into categories, suggests a study examining the association of ultraprocessed animal products and beverages with cognitive functions.

UPF categories needed to identify foods linked to cognitive impairment

21 May 2025

Hypoglycaemia often occurs in insulin-treated hyperkalemia patients

21 May 2025 by

The use of intravenous (IV) insulin for managing hyperkalemia in hospitalized patients may lead to hypoglycaemia, which occurs more frequently in those with kidney-related conditions, according to a Singapore study.

Hypoglycaemia often occurs in insulin-treated hyperkalemia patients

21 May 2025

Obesity ups risk of irritable bowel syndrome

21 May 2025

General and central obesity are both significant risk factors for the development of irritable bowel syndrome (IBS), suggests a study.

Obesity ups risk of irritable bowel syndrome

21 May 2025

TrUST study heralds new era for TB diagnosis

21 May 2025 by

A suite of deep learning (DL) models to automate tuberculosis (TB) risk assessment from lung ultrasound (LUS) images fulfils the WHO criteria for a sputum-free TB triage test and outwits human experts in the TrUST study.

TrUST study heralds new era for TB diagnosis

21 May 2025

Stroke risk high after transient ischaemic attack

21 May 2025

Patients with transient ischaemic attack (TIA) or minor stroke are at increased risk of subsequent stroke, according to systematic review and meta-analysis.

Stroke risk high after transient ischaemic attack

21 May 2025

How does an AI-based angiography system fare in PCI?

21 May 2025 by

In the FLASH study, a recently developed artificial intelligence-based quantitative coronary angiography (AI-QCA) system is noninferior to optical coherence tomography (OCT)-guided percutaneous coronary intervention (PCI) in achieving optimal post-PCI minimal stent area (MSA) in patients with less complex coronary artery disease (CAD).

How does an AI-based angiography system fare in PCI?

21 May 2025

Wearable device tracks infant milk intake during breastfeeding

20 May 2025 by

A compact, unobtrusive wearable device can accurately measure expressed milk volume during breastfeeding in real time for better infant care.

Wearable device tracks infant milk intake during breastfeeding

20 May 2025

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Survival benefits of trastuzumab deruxtecan in patients with previously treated HER2-low mBC

Survival benefits of trastuzumab deruxtecan in patients with previously treated HER2-low mBC

Apixaban a safe oral anticoagulant choice for VTE patients

Apixaban a safe oral anticoagulant choice for VTE patients

Mild low birthweight carries increased childhood hypertension risk

Mild low birthweight carries increased childhood hypertension risk

UPF categories needed to identify foods linked to cognitive impairment

UPF categories needed to identify foods linked to cognitive impairment

Hypoglycaemia often occurs in insulin-treated hyperkalemia patients

Hypoglycaemia often occurs in insulin-treated hyperkalemia patients

Obesity ups risk of irritable bowel syndrome

Obesity ups risk of irritable bowel syndrome

TrUST study heralds new era for TB diagnosis

TrUST study heralds new era for TB diagnosis

Stroke risk high after transient ischaemic attack

Stroke risk high after transient ischaemic attack

How does an AI-based angiography system fare in PCI?

How does an AI-based angiography system fare in PCI?

Wearable device tracks infant milk intake during breastfeeding

Wearable device tracks infant milk intake during breastfeeding