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Early initiation of a soluble guanylate cyclase stimulator in an elderly patient with refractory HFrEF
Early initiation of a soluble guanylate cyclase stimulator in an elderly patient with refractory HFrEF
23 Apr 2025 byDr. Cyril Ko, Specialist in Cardiology, Private practice, Hong Kong

The patient was an 80-year-old male with multiple comorbidities, including diabetes mellitus controlled with a sodium-glucose cotransporter-2 inhibitor (SGLT2i), hypertension and coronary artery disease, for which he underwent stenting in October 2023. He also had a pacemaker implanted for heart block. His left ventricular ejection fraction (LVEF) ranged between 40–50 percent. For several years, he had been managed as an outpatient for mild heart failure (HF) symptoms and maintained independence in activities of daily living (ADL).

Early initiation of a soluble guanylate cyclase stimulator in an elderly patient with refractory HFrEF
23 Apr 2025
Etripamil nasal spray safe, effective against PSVT
Etripamil nasal spray safe, effective against PSVT
19 Apr 2025
LBB performs better than standard BiV pacing for CRT in chronic heart failure
LBB performs better than standard BiV pacing for CRT in chronic heart failure
17 Apr 2025 byJairia Dela Cruz

For chronic heart failure patients requiring cardiac resynchronization therapy (CRT), the use of left bundle branch (LBB) pacing yields superior clinical outcomes compared with the traditional biventricular (BiV) pacing, as shown in the results of the HeartSync-LBBP trial.

LBB performs better than standard BiV pacing for CRT in chronic heart failure
17 Apr 2025