News & Updates

More walking, less low back pain issues

Walking a longer distance or for a longer time can reduce the risk of developing chronic low back pain.

Sexual function reduced in people with multiple sclerosis

People with multiple sclerosis (MS) tend to experience a lower sexual function (SF) than healthy individuals, reports a study. Age, depression, disease duration, and the Expanded Disability Status Scale (EDSS) influence SF.

POIS treatment must consider symptoms, outcomes: study

Examining the symptoms experienced by patients with postorgasmic illness syndrome (POIS) can help improve treatment and resolve these symptoms, suggests a study.

Vedolizumab vs adalimumab: Which works better for CD?

Treatment with vedolizumab exhibits equivalent rates of response and mucosal healing but higher odds of drug persistence and achieving clinical remission compared with adalimumab in biologic-naïve patients with Crohn’s disease (CD), reports a study in a real-world setting.

Rehydration strategies yield similar mortality outcome in kids with malnutrition, gastroenteritis

In the treatment of children with severe acute malnutrition and gastroenteritis, those who undergo oral rehydration therapy have similar mortality rates as those who receive intravenous rehydration therapy, according to a study.

Herpes zoster encephalitis in two patients with kidney disease: Diagnostic and therapeutic challenges

Case 1: A 73-year-old woman with diabetes and end-stage renal disease receiving acyclovir treatment for herpes zoster (HZ) presented with altered mental status. Laboratory tests and brain CT were unremarkable. What is the diagnosis? Acyclovir neurotoxicity or HZ encephalitis?

Case 2: A 63-year-old man with sudden onset of rapidly progressive glomerulonephritis presented with severe acute confusion 1 month after initiation of high-dose immunosuppressants and corticosteroid. Physical examination found HZ vesicles at L1 dermatomes and lumbar puncture confirmed HZ encephalitis. Treatment dilemma: To continue immunosuppressive therapy to save the kidney, or taper off to save the brain and cognition?

Scheduled lorazepam-based regimens superior to haloperidol alone for agitated delirium at end of life

Proactive use of scheduled lorazepam or lorazepam plus haloperidol is superior to haloperidol alone in managing refractory agitated delirium in patients with advanced cancer in the palliative care setting, according to results of a multicentre randomized clinical trial (RCT) conducted in Taiwan and the US.

Hidradenitis suppurativa patients vulnerable to mental disorders

Patients with hidradenitis suppurativa (HS) face increased risks of depression and anxiety, as reported in a study.

Healthy behaviours may prevent death in cirrhosis patients

Keeping a healthy lifestyle such as having a balanced diet, regular exercise, and quality sleep may provide survival benefits to patients with cirrhosis, suggests a study.