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Which antibiotic regimen is best for paediatric appendicitis?

21 Sep 2025 by

The use of antibiotics to treat paediatric appendicitis should target Escherichia coli and anaerobes, suggests a study. Two other bacteria are also present in about a fourth of the cultures, namely viridans group streptococci (VGS) and pseudomonas.

Which antibiotic regimen is best for paediatric appendicitis?

21 Sep 2025

Multimodal AI system improves accuracy in identifying interstitial pneumonia

19 Sep 2025 by

The multimodal artificial intelligence (AI) algorithm that combines computed tomography (CT) and histopathological images improves diagnostic accuracy, consistency, and confidence of pathologists in identifying usual interstitial pneumonia (UIP) in patients with resected lung specimens, reports a study.

Multimodal AI system improves accuracy in identifying interstitial pneumonia

19 Sep 2025

Clinical research in non-university public hospitals correlated with improved patient outcomes

19 Sep 2025 by

More than 10 percent of full-time clinicians in Hong Kong’s non-university public hospitals engaged in original research as principal investigators (PIs), contributing to nearly one-third of the city’s peer-reviewed studies published in 2016–2021. Their clinical research activity is correlated with improved patient outcomes.

Clinical research in non-university public hospitals correlated with improved patient outcomes

19 Sep 2025

Carbapenem resistance surges in HK: New IMPACT data underscore urgency

16 Sep 2025

Antimicrobial resistance (AMR), particularly carbapenem-resistant Gram-negative bacteria (CR-GNB), continues to accelerate across Hong Kong, according to Reducing bacterial resistance with IMPACT (Interhospital Multi-disciplinary Programme on Antimicrobial ChemoTherapy), 6^th edition, Hong Kong, published in 2025. This update provides new surveillance data and local clinical recommendations, and underscores the critical need for robust stewardship as CR-GNB infections emerge as a major threat to patient care.

Carbapenem resistance surges in HK: New IMPACT data underscore urgency

16 Sep 2025

Routine H pylori screening in acute MI patients of no benefit

13 Sep 2025

Routine screening for Helicobacter pylori infection in patients with acute myocardial infarction (MI) does not help lower the risk of upper gastrointestinal bleeding, according to a crossover trial.

Routine H pylori screening in acute MI patients of no benefit

13 Sep 2025

Sotrovimab for COVID-19 pneumonia lowers risk of death in specific subgroup

10 Sep 2025 by

In the treatment of hospitalized patients with COVID-19 pneumonia, the use of the neutralizing monoclonal antibody sotrovimab in addition to usual care reduces mortality but only in the subgroup of those with a high baseline serum SARS-CoV-2 antigen concentration, according to the open-label RECOVERY trial.

Sotrovimab for COVID-19 pneumonia lowers risk of death in specific subgroup

10 Sep 2025

Neuropsychiatric AEs resolve after switch to doravirine-based ARV regimens

10 Sep 2025 by

Switching to a doravirine-based ARV regimen resolves neuropsychiatric AEs that were ongoing during a prior efavirenz-based regimen in DRIVE-AHEAD, with few events persisting 96 weeks after switching — a finding also seen in DRIVE-FORWARD, as shown in post hoc analyses of the OLEs of the two phase III trials

Neuropsychiatric AEs resolve after switch to doravirine-based ARV regimens

10 Sep 2025

Antihistamine nasal spray a promising prophylactic treatment against SARS-CoV-2

08 Sep 2025 by

The use of the antihistamine nasal spray azelastine may help prevent SARS-CoV-2 respiratory infections, as shown in a phase II study.

Antihistamine nasal spray a promising prophylactic treatment against SARS-CoV-2

08 Sep 2025

HK data: Clozapine may increase infection risk in schizophrenia

02 Sep 2025 by

Clozapine is associated with a moderately increased risk of infection vs olanzapine in patients with schizophrenia in Hong Kong, with the association being notably stronger in older age groups, according to researchers from the Department of Family Medicine and Primary Care at the University of Hong Kong (HKU).

HK data: Clozapine may increase infection risk in schizophrenia

02 Sep 2025

Respiratory virus ups mortality risk in kids undergoing LT

01 Sep 2025

Detection of respiratory viruses in children with severe hepatocellular dysfunction during the peri-liver transplant period appears to increase the risk of death and postoperative surgical complications, reveals a recent study.

Respiratory virus ups mortality risk in kids undergoing LT

01 Sep 2025

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Which antibiotic regimen is best for paediatric appendicitis?

Which antibiotic regimen is best for paediatric appendicitis?

Multimodal AI system improves accuracy in identifying interstitial pneumonia

Multimodal AI system improves accuracy in identifying interstitial pneumonia

Clinical research in non-university public hospitals correlated with improved patient outcomes

Clinical research in non-university public hospitals correlated with improved patient outcomes

Carbapenem resistance surges in HK: New IMPACT data underscore urgency

Carbapenem resistance surges in HK: New IMPACT data underscore urgency

Routine H pylori screening in acute MI patients of no benefit

Routine H pylori screening in acute MI patients of no benefit

Sotrovimab for COVID-19 pneumonia lowers risk of death in specific subgroup

Sotrovimab for COVID-19 pneumonia lowers risk of death in specific subgroup

Neuropsychiatric AEs resolve after switch to doravirine-based ARV regimens

Neuropsychiatric AEs resolve after switch to doravirine-based ARV regimens

Antihistamine nasal spray a promising prophylactic treatment against SARS-CoV-2

Antihistamine nasal spray a promising prophylactic treatment against SARS-CoV-2

HK data: Clozapine may increase infection risk in schizophrenia

HK data: Clozapine may increase infection risk in schizophrenia

Respiratory virus ups mortality risk in kids undergoing LT

Respiratory virus ups mortality risk in kids undergoing LT