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Navepegritide tied to increased growth velocity in children with ACH

23 Aug 2025 by

Once-weekly treatment with navepegritide was associated with significantly improved annualized growth velocity (AGV) in children with achondroplasia (ACH) compared with placebo, according to results from the pivotal ApproaCH trial presented at ENDO 2025.

Navepegritide tied to increased growth velocity in children with ACH

23 Aug 2025

Several factors tied to treatment failure in children starting first-line ART

22 Aug 2025 by

In children living with HIV initiating antiretroviral therapy (ART), factors such as the ART regimen, age, BMI, and baseline CD4 count, among others, can predict treatment failure, according to a study.

Several factors tied to treatment failure in children starting first-line ART

22 Aug 2025

Can pregnant, lactating people use lenacapavir to prevent HIV infection?

19 Aug 2025 by

The use of lenacapavir is highly efficacious in pregnant and lactating people (PLP), with zero participants acquiring HIV, as shown by the results of the PURPOSE 1 study.

Can pregnant, lactating people use lenacapavir to prevent HIV infection?

19 Aug 2025

Original New Drug Application Approvals by US FDA (16-31 July 2025)

19 Aug 2025

New drug applications approved by US FDA as of 16-31 July 2025 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (16-31 July 2025)

19 Aug 2025

Original-New-Drug-Application-Approvals-by-US-FDA--1-15-July-2025

19 Aug 2025

New drug applications approved by US FDA as of 1-15 July 2025 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original-New-Drug-Application-Approvals-by-US-FDA--1-15-July-2025

19 Aug 2025

Unhealthy weight in parents before pregnancy tied to adverse birth outcomes

17 Aug 2025

The preconception weight of parents, whether too low or too high, contributes to the risk of adverse birth outcomes, including perinatal death and birth defects, according to a study.

Unhealthy weight in parents before pregnancy tied to adverse birth outcomes

17 Aug 2025

Oseltamivir for influenza helps reduce neuropsychiatric events

15 Aug 2025

The use of oseltamivir for treating influenza episodes in children appears to lower the risk of serious neuropsychiatric events, according to a retrospective cohort study.

Oseltamivir for influenza helps reduce neuropsychiatric events

15 Aug 2025

Study supports early antibiotic suspension in kids with cancer, febrile neutropenia

14 Aug 2025 by

The E-STOP trial presented at ESHRE 2025 supports early antibiotic suspension in paediatric patients with cancer and febrile neutropenia (FN).

Study supports early antibiotic suspension in kids with cancer, febrile neutropenia

14 Aug 2025

Peg-filgrastim reduces neutropenia in children with solid tumours

13 Aug 2025

The incidence of febrile neutropenia (FN) is significantly lesser in children with solid tumours receiving pegylated filgrastim as primary prophylaxis following chemotherapy than in those assigned to filgrastim alone, reports a study. Moreover, no adverse events attributed to the study drug have been observed.

Peg-filgrastim reduces neutropenia in children with solid tumours

13 Aug 2025

F/TAF plus cobicistat-boosted PIs maintained virologic suppression in children with HIV

13 Aug 2025 by

Treatment with emtricitabine/tenofovir alafenamide (F/TAF) and cobicistat-boosted atazanavir (ATV/c) or darunavir (DRV/c) maintained high rates of virologic suppression through 48 weeks in children living with HIV, based on two cohorts of the GS-US-216-0128 study presented at IAS 2025.

F/TAF plus cobicistat-boosted PIs maintained virologic suppression in children with HIV

13 Aug 2025

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Navepegritide tied to increased growth velocity in children with ACH

Navepegritide tied to increased growth velocity in children with ACH

Several factors tied to treatment failure in children starting first-line ART

Several factors tied to treatment failure in children starting first-line ART

Can pregnant, lactating people use lenacapavir to prevent HIV infection?

Can pregnant, lactating people use lenacapavir to prevent HIV infection?

Original New Drug Application Approvals by US FDA (16-31 July 2025)

Original New Drug Application Approvals by US FDA (16-31 July 2025)

Original-New-Drug-Application-Approvals-by-US-FDA--1-15-July-2025

Original-New-Drug-Application-Approvals-by-US-FDA--1-15-July-2025

Unhealthy weight in parents before pregnancy tied to adverse birth outcomes

Unhealthy weight in parents before pregnancy tied to adverse birth outcomes

Oseltamivir for influenza helps reduce neuropsychiatric events

Oseltamivir for influenza helps reduce neuropsychiatric events

Study supports early antibiotic suspension in kids with cancer, febrile neutropenia

Study supports early antibiotic suspension in kids with cancer, febrile neutropenia

Peg-filgrastim reduces neutropenia in children with solid tumours

Peg-filgrastim reduces neutropenia in children with solid tumours

F/TAF plus cobicistat-boosted PIs maintained virologic suppression in children with HIV

F/TAF plus cobicistat-boosted PIs maintained virologic suppression in children with HIV