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Adjunctive lumateperone improves symptoms in major depressive disorder

23 Dec 2025

Lumateperone plus antidepressant therapy (ADT) demonstrates clinically meaningful improvements in depression symptoms and disease severity relative to placebo plus ADT, according to a study.

Adjunctive lumateperone improves symptoms in major depressive disorder

23 Dec 2025

Two DOACs show similar bleeding risks in head-to-head VTE trial

23 Dec 2025 by

In a post hoc analysis of the RENOVE trial, the direct oral anticoagulants (DOACs) rivaroxaban and apixaban demonstrate comparable risks of clinically relevant bleeding (CRB) and recurrent venous thromboembolism (VTE). These were observed across the crude, adjusted, and IPTW* analyses.

Two DOACs show similar bleeding risks in head-to-head VTE trial

23 Dec 2025

Air conditioning may prevent heat-related deaths among seniors

23 Dec 2025

In nursing homes, air conditioning helps lower mortality among older adults on days when the heat index is extremely high, according to a case-crossover study in Canada.

Air conditioning may prevent heat-related deaths among seniors

23 Dec 2025

Domperidone for lactation support does not carry risk of new-onset psychosis

22 Dec 2025

Postpartum initiation of domperidone to support lactation does not appear to increase the risk of new-onset psychosis or emergency department (ED) visits or hospital admissions with mental health diagnoses, according to a retrospective study.

Domperidone for lactation support does not carry risk of new-onset psychosis

22 Dec 2025

Haemophilia B gene therapy benefit sustained through 5 years

22 Dec 2025 by

The final 5-year data from the phase III HOPE-B study demonstrated consistently low annualized bleeding rates and durable endogenous factor IX expression in haemophilia B patients, with no late hepatotoxicity or treatment-related oncogenicity observed.

Haemophilia B gene therapy benefit sustained through 5 years

22 Dec 2025

Drug-drug interactions rife among patients with haematologic malignancy

22 Dec 2025

A recent study has shown the prevalence of drug-drug interactions (DDIs) among hospitalized patients with haematologic malignancies, with the occurrence increasing alongside the number of medications administered.

Drug-drug interactions rife among patients with haematologic malignancy

22 Dec 2025

Insulin glargine improves glycaemic control in T2D patients in India

22 Dec 2025 by

Findings from the prospective PRIMARY-INDIA study presented at ATTD-Asia 2025 show clinically meaningful improvements in glycaemic control with insulin glargine in individuals with type 2 diabetes (T2D) in primary care settings, with a consistent safety profile.

Insulin glargine improves glycaemic control in T2D patients in India

22 Dec 2025

Body dissatisfaction may drive development of eating disorder, depressive symptoms

22 Dec 2025

Body dissatisfaction in adolescence may directly contribute to an increase in symptoms of eating disorder and depression, according to a study.

Body dissatisfaction may drive development of eating disorder, depressive symptoms

22 Dec 2025

Insulin glargine/lixisenatide enhances T2DM control in real world

21 Dec 2025 by

Switching to insulin glargine/lixisenatide effectively lowers glucose levels in overweight adults with uncontrolled type 2 diabetes mellitus (T2DM), according to real-world data.

Insulin glargine/lixisenatide enhances T2DM control in real world

21 Dec 2025

DBT outclasses SSRI/M in reducing suicide among borderline personality disorder patients

21 Dec 2025

Six months of dialectical behaviour therapy (DBT) is more efficacious than 6 months of selective serotonin reuptake inhibitors with clinical management (SSRI/M) in the reduction of suicide-related events (SREs) and nonsuicidal self-injury (NSSI) behaviours in patients with borderline personality disorder, reports a study.

DBT outclasses SSRI/M in reducing suicide among borderline personality disorder patients

21 Dec 2025

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Adjunctive lumateperone improves symptoms in major depressive disorder

Adjunctive lumateperone improves symptoms in major depressive disorder

Two DOACs show similar bleeding risks in head-to-head VTE trial

Two DOACs show similar bleeding risks in head-to-head VTE trial

Air conditioning may prevent heat-related deaths among seniors

Air conditioning may prevent heat-related deaths among seniors

Domperidone for lactation support does not carry risk of new-onset psychosis

Domperidone for lactation support does not carry risk of new-onset psychosis

Haemophilia B gene therapy benefit sustained through 5 years

Haemophilia B gene therapy benefit sustained through 5 years

Drug-drug interactions rife among patients with haematologic malignancy

Drug-drug interactions rife among patients with haematologic malignancy

Insulin glargine improves glycaemic control in T2D patients in India

Insulin glargine improves glycaemic control in T2D patients in India

Body dissatisfaction may drive development of eating disorder, depressive symptoms

Body dissatisfaction may drive development of eating disorder, depressive symptoms

Insulin glargine/lixisenatide enhances T2DM control in real world

Insulin glargine/lixisenatide enhances T2DM control in real world

DBT outclasses SSRI/M in reducing suicide among borderline personality disorder patients

DBT outclasses SSRI/M in reducing suicide among borderline personality disorder patients