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Capivasertib‒fulvestrant combo delays second progression, chemo in advanced breast cancer
20 May 2026
byStephen Padilla
The addition of capivasertib to fulvestrant improves time to second progression (PFS2) and time to first subsequent chemotherapy or death (TTFSC) in PIK3CA/AKT1/PTEN-altered patients with HR+/HER2- advanced breast cancer and the overall population, suggesting a clinically meaningful benefit when compared with placebo plus fulvestrant, as shown in the phase III CAPItello-291 trial.
Capivasertib‒fulvestrant combo delays second progression, chemo in advanced breast cancer
20 May 2026
Lecanemab continues to delay progression in AD at 4 years
20 May 2026
byAudrey Abella
The 48-month analysis of the global phase III Clarity AD study shows that lecanemab continues to deliver benefit and delay progression in early Alzheimer's disease (AD).







