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X-linked hypophosphataemia: Multidisciplinary care needed, targeted therapy effectively normalizes phosphate homeostasis

11 Dec 2025

Management of X-linked hypophosphataemia (XLH) has evolved in the past few years following the availability of burosumab, a fully humanized monoclonal antibody targeting circulating fibroblast growth factor 23 (FGF23), which has changed the landscape of XLH management, a panel of experts who spoke at EDM HK 2025 concurred.

X-linked hypophosphataemia: Multidisciplinary care needed, targeted therapy effectively normalizes phosphate homeostasis

11 Dec 2025

Epilepsy risk elevated in children with congenital Zika syndrome

10 Dec 2025 by

New research suggests that in-utero exposure to Zika virus (ZIKV) alone does not increase the risk of epilepsy in early childhood, and the risk increase is limited to children who develop congenital Zika syndrome.

Epilepsy risk elevated in children with congenital Zika syndrome

10 Dec 2025

Antimicrobial use rises following TNFi initiation in PsA patients

10 Dec 2025

A recent study has noted a temporary increase in antimicrobial use following initiation of tumour necrosis factor inhibitor (TNFi) treatment, with no significant risk in serious infections, among patients with psoriatic arthritis (PsA).

Antimicrobial use rises following TNFi initiation in PsA patients

10 Dec 2025

Whole foods, Mediterranean diet help improve endothelial function

10 Dec 2025 by

Eating whole foods such as fruits and vegetables regularly, as well as following a Mediterranean diet, can enhance endothelial function as measured by flow-mediated dilation (FMD), suggests a study.

Whole foods, Mediterranean diet help improve endothelial function

10 Dec 2025

Does palmitoleic acid supplementation reduce hs-CRP in adults?

10 Dec 2025

Supplementation with palmitoleic acid (POA) 500 or 1,000 mg/day does not appear to substantially reduce high-sensitivity C-reactive protein (hs-CRP) or change other biomarkers in adults relative to placebo, reports a study.

Does palmitoleic acid supplementation reduce hs-CRP in adults?

10 Dec 2025

Nirsevimab cuts RSV burden in newborns

10 Dec 2025 by

A retrospective study from Italy shows an association between nirsevimab prophylaxis and a lower risk of respiratory syncytial virus (RSV) hospitalizations and a milder disease course.

Nirsevimab cuts RSV burden in newborns

10 Dec 2025

Engasertib shows promise in hereditary haemorrhagic telangiectasia

10 Dec 2025

In the treatment of patients with hereditary haemorrhagic telangiectasia (HHT), use of the novel allosteric, selective AKT inhibitor engasertib appears to be safe and reduce the frequency and duration of epistaxis, according to a proof-of-concept study.

Engasertib shows promise in hereditary haemorrhagic telangiectasia

10 Dec 2025

Plasma p-tau217 detects Alzheimer's disease in preclinical stage

09 Dec 2025 by

Plasma phosphorylated tau 217 (p-tau217) can identify pathological changes characteristic of Alzheimer’s disease (AD) in older adults without cognitive impairment, according to a meta-analysis.