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Women with opioid use disorder (OUD) treated with buprenorphine during pregnancy had significantly lower rates of adverse maternal and infant outcomes than those who did not receive treatment, according to a study presented at PAS 2025.
In Singaporean women, improved physical performance appears to reduce the risk of depression during midlife, whereas worsening menopausal symptoms and pelvic floor dysfunction contribute to a risk increase, according to a local study.
During early pregnancy, high levels of maternal estradiol (E2) appear to contribute to altered glucose metabolism and greater metabolic risks in children conceived via in vitro fertilization (IVF), reports a recent study.
IBP-9414, a live biotherapeutic product (LBP), delivers gastrointestinal (GI) and mortality benefits in very low birth weight (VLBW) infants (BW 500–1,500g) born between 23 and 32 weeks gestational age in the phase III Connection study presented at PAS 2025.
Blood pressure values and ventricular mass tend to be more elevated among women with previous de novo pre-eclampsia (PE) than those with previous normal pregnancies, according to a study.
Postpartum haemorrhage most commonly occurs due to uterine atony, according to a systematic review and meta-analysis. Other causes include genital tract trauma, retained placenta, abnormal placentation, and coagulopathy.
Among patients with polycystic ovary syndrome (PCOS), a high triglyceride-glucose (TyG) index appears to be associated with adverse metabolic trajectories and pregnancy outcomes, according to a study.
Treatment with tenofovir alafenamide (TAF) is generally safe and effective for the prevention of hepatitis B virus (HBV) mother-to-child transmission (MTCT), reports a study, noting that the expected 8-week prenatal duration is feasible.
In the final overall survival (OS) analysis of the phase III MIRASOL trial, the survival benefit previously reported with the antibody drug conjugate mirvetuximab soravtansine (MIRV) remains superior to investigator’s choice chemotherapy (ICC) for the treatment of folate receptor alpha-positive, platinum-resistant ovarian cancer (FRα+ PROC).
Greater intrinsic motivation for engaging in healthy lifestyle behaviours appears to promote long-term postpartum weight reduction and may be a promising target for interventions, suggests a study.
