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Should O2 exposure be reduced in critically ill patients on MV, O2?

28 Aug 2025 by

Findings from the UK-ROX* trial do not support reducing oxygen (O2) exposure by targeting a peripheral O2 saturation (SpO2) of 90 percent in adult patients receiving mechanical ventilation (MV) and supplemental O2 in the intensive care unit (ICU).

Should O2 exposure be reduced in critically ill patients on MV, O2?

28 Aug 2025

Adequate sleep, exercise reduce mortality in individuals with depression

28 Aug 2025

Getting enough sleep, engaging in high levels of physical activity, and cutting sedentary time appear to lower the risk of mortality in people with depression, according to a study.

Adequate sleep, exercise reduce mortality in individuals with depression

28 Aug 2025

Statin exposure associated with longer OS in apalutamide-treated patients with advanced prostate cancer

28 Aug 2025 by

A study using individual patient data from the SPARTAN and TITAN randomized clinical trials has found that statin exposure was associated with superior overall survival (OS) among all patients with advanced prostate cancer (PC) who were treated with apalutamide.

Statin exposure associated with longer OS in apalutamide-treated patients with advanced prostate cancer

28 Aug 2025

Does adjuvant aspirin have a protective effect in resected PIK3CA-mutant colon cancer?

28 Aug 2025 by

Adjuvant aspirin is associated with clinically relevant disease-free survival (DFS) and time to disease recurrence (TTR) improvements, according to a phase III randomized, placebo-controlled trial.

Does adjuvant aspirin have a protective effect in resected PIK3CA-mutant colon cancer?

28 Aug 2025

Certain nonsurgical interventions for chronic low back pain may offer sustained benefits

27 Aug 2025

For individuals with chronic low back pain, nonsurgical interventions such as cognitive behavioural therapy (CBT), mindfulness, exercise, and multidisciplinary care can help reduce pain intensity and disability in the long term, according to a systematic review and meta-analysis.

Certain nonsurgical interventions for chronic low back pain may offer sustained benefits

27 Aug 2025

Stapokibart makes the grade in severe chronic rhinosinusitis with nasal polyps

27 Aug 2025 by

In Asian patients with severe chronic rhinosinusitis with nasal polyps who are receiving daily intranasal corticosteroid, add-on treatment with the novel monoclonal antibody stapokibart helps shrink polyp size and bring down the severity of symptoms, as shown in the phase III CROWNS-2 study conducted in China.

Stapokibart makes the grade in severe chronic rhinosinusitis with nasal polyps

27 Aug 2025

Canagliflozin lowers HbA1c levels in children with T2DM

27 Aug 2025

Treatment with canagliflozin significantly reduces haemoglobin A1c (HbA1c) in children and adolescents with type 2 diabetes mellitus (T2DM), with a safety profile comparable to that seen in adults, results of a phase III trial have shown.

Canagliflozin lowers HbA1c levels in children with T2DM

27 Aug 2025

Cell harvesting device delivers repigmentation in stable vitiligo lesions

27 Aug 2025 by

A cell harvesting device that prepares autologous skin cell suspension (ASCS) offers a simple yet accessible technique for melanocyte transplantation in patients with vitiligo, a study has shown.

Cell harvesting device delivers repigmentation in stable vitiligo lesions

27 Aug 2025

TyG index linked to hypertension incidence

27 Aug 2025

The triglyceride-glucose (TyG) index can be used to predict the incidence of hypertension, according to a study involving a population-based sample of Japanese men.

TyG index linked to hypertension incidence

27 Aug 2025

Guided internet-based CBT shows promise in bulimia nervosa

27 Aug 2025

Therapist-guided, internet-based cognitive behaviour therapy (CBT) helps reduce the symptoms of bulimia nervosa in women, as shown in a study.

Guided internet-based CBT shows promise in bulimia nervosa

27 Aug 2025

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Should O2 exposure be reduced in critically ill patients on MV, O2?

Should O2 exposure be reduced in critically ill patients on MV, O2?

Adequate sleep, exercise reduce mortality in individuals with depression

Adequate sleep, exercise reduce mortality in individuals with depression

Statin exposure associated with longer OS in apalutamide-treated patients with advanced prostate cancer

Statin exposure associated with longer OS in apalutamide-treated patients with advanced prostate cancer

Does adjuvant aspirin have a protective effect in resected PIK3CA-mutant colon cancer?

Does adjuvant aspirin have a protective effect in resected PIK3CA-mutant colon cancer?

Certain nonsurgical interventions for chronic low back pain may offer sustained benefits

Certain nonsurgical interventions for chronic low back pain may offer sustained benefits

Stapokibart makes the grade in severe chronic rhinosinusitis with nasal polyps

Stapokibart makes the grade in severe chronic rhinosinusitis with nasal polyps

Canagliflozin lowers HbA1c levels in children with T2DM

Canagliflozin lowers HbA1c levels in children with T2DM

Cell harvesting device delivers repigmentation in stable vitiligo lesions

Cell harvesting device delivers repigmentation in stable vitiligo lesions

TyG index linked to hypertension incidence

TyG index linked to hypertension incidence

Guided internet-based CBT shows promise in bulimia nervosa

Guided internet-based CBT shows promise in bulimia nervosa