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Can gut microbiome composition predict response to pembrolizumab +/- chemo in treatment-naïve mNSCLC?
23 Sep 2025
byNatalia Reoutova
Research findings from Yonsei Cancer Center in South Korea, presented at European Society for Medical Oncology Targeted Anticancer Therapies Asia Congress (ESMO TAT Asia) 2025, suggest a correlation between butyrate-producing Faecalibacterium enrichment and clinical response to pembrolizumab with or without chemotherapy in treatment-naïve patients with metastatic non-small-cell lung cancer (mNSCLC).
Can gut microbiome composition predict response to pembrolizumab +/- chemo in treatment-naïve mNSCLC?
23 Sep 2025
PORTEC-3: Adjuvant chemoradiotherapy improves 10-year OS in high-risk endometrial cancer
15 Sep 2025
byKanas Chan
Adjuvant chemoradiotherapy (CRT) improves both 10-year overall survival (OS) and recurrence-free survival (RFS) in women with high-risk endometrial cancer vs pelvic radiotherapy alone, with the most clinically relevant benefit observed in p53 abnormal cancers, according to the 10-year analysis of the phase III PORTEC-3 trial.