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PSMA-targeted radioligand therapy improves survival in patients with mCRPC

10 Oct 2025 by

A 63-year-old male with hypertension, hyperlipidaemia and diabetes was diagnosed with metastatic prostate cancer with lumbar spine metastases in 2018. He initially presented with lower urinary tract symptoms and markedly elevated prostate-specific antigen (PSA) of up to 85.3 ng/mL. He was started on luteinizing hormone–releasing hormone (LHRH) antagonist as androgen deprivation therapy (ADT) with good response of PSA drop to 13.4 mg/mL.

PSMA-targeted radioligand therapy improves survival in patients with mCRPC

10 Oct 2025

[Infographics] Two patients with dyslipidaemia treated with oral bempedoic acid + ezetimibe FDC

10 Oct 2025 by

Dr Walter Wai-Chee Chan's (Specialist in Cardiology in Hong Kong) cases: one patient with statin-induced autoimmune myositis, and another patient with uncontrolled LDL-C despite maximally tolerated statin + ezetimibe. Find out how these patients responded to and tolerated oral bempedoic acid + ezetimibe fixed-dose combination (FDC) treatment.

[Infographics] Two patients with dyslipidaemia treated with oral bempedoic acid + ezetimibe FDC

10 Oct 2025

Memantine shows therapeutic potential in children with ASD

09 Oct 2025 by

Treatment with memantine may improve social functioning in children with autism spectrum disorder (ASD), as shown in a small study.

Memantine shows therapeutic potential in children with ASD

09 Oct 2025

Model predicts cardiomyopathy risk in childhood cancer survivors

09 Oct 2025

Researchers have recently developed prediction models with highest-to-date performance to estimate the 10-year risk of cardiomyopathy in long-term survivors of childhood cancer.

Model predicts cardiomyopathy risk in childhood cancer survivors

09 Oct 2025

Tirzepatide proves safety, efficacy in T1D in real world

09 Oct 2025 by

The use of tirzepatide in a real-world setting demonstrates a favourable safety profile and results in weight loss, lower insulin requirements, and better glycaemic measurements among patients with type 1 diabetes (T1D), as shown in a study presented at EASD 2025.

Tirzepatide proves safety, efficacy in T1D in real world

09 Oct 2025

Does anticoagulant use improve survival in PAH?

09 Oct 2025

The use of anticoagulant therapy offers no survival benefit in patients with pulmonary arterial hypertension (PAH), a recent study has shown.

Does anticoagulant use improve survival in PAH?

09 Oct 2025

Oral disorders prevalent in patients with diabetes

09 Oct 2025 by

A study reports a strong correlation between diabetes and oral pathologies, particularly malignancies and periodontal disease.

Oral disorders prevalent in patients with diabetes

09 Oct 2025

Elevated serum uric acid tied to high-risk coronary artery plaques

09 Oct 2025

Individuals with increased serum uric acid have a higher likelihood of showing high-risk coronary artery plaques on coronary CT angiography (CCTA), as reported in a retrospective study.

Elevated serum uric acid tied to high-risk coronary artery plaques

09 Oct 2025

PPIs unlikely linked to increased stroke risk in patients taking antithrombotics

09 Oct 2025 by

Researchers at the University of Hong Kong (HKU) have found that the risk of ischaemic stroke is not increased in patients on proton-pump inhibitor (PPI) monotherapy, but is increased in those coprescribed with antithrombotic drugs, possibly due to their underlying higher risk profiles.

PPIs unlikely linked to increased stroke risk in patients taking antithrombotics

09 Oct 2025

Old drug, new purpose: Low-dose ATG may halt T1D progression in youths

08 Oct 2025 by

The old immunomodulatory drug antithymocyte globulin (ATG), administered at a low dose, can safely reduce the loss of beta-cell function in young people with recent-onset type 1 diabetes (T1D), as shown in the phase II MELD-ATG trial.

Old drug, new purpose: Low-dose ATG may halt T1D progression in youths

08 Oct 2025

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PSMA-targeted radioligand therapy improves survival in patients with mCRPC

PSMA-targeted radioligand therapy improves survival in patients with mCRPC

[Infographics] Two patients with dyslipidaemia treated with oral bempedoic acid + ezetimibe FDC

[Infographics] Two patients with dyslipidaemia treated with oral bempedoic acid + ezetimibe FDC

Memantine shows therapeutic potential in children with ASD

Memantine shows therapeutic potential in children with ASD

Model predicts cardiomyopathy risk in childhood cancer survivors

Model predicts cardiomyopathy risk in childhood cancer survivors

Tirzepatide proves safety, efficacy in T1D in real world

Tirzepatide proves safety, efficacy in T1D in real world

Does anticoagulant use improve survival in PAH?

Does anticoagulant use improve survival in PAH?

Oral disorders prevalent in patients with diabetes

Oral disorders prevalent in patients with diabetes

Elevated serum uric acid tied to high-risk coronary artery plaques

Elevated serum uric acid tied to high-risk coronary artery plaques

PPIs unlikely linked to increased stroke risk in patients taking antithrombotics

PPIs unlikely linked to increased stroke risk in patients taking antithrombotics

Old drug, new purpose: Low-dose ATG may halt T1D progression in youths

Old drug, new purpose: Low-dose ATG may halt T1D progression in youths