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Pharmacists cut inappropriate antipsychotic use upon discharge

27 Jun 2025

A pharmacist-driven intervention contributes to a reduction in inappropriate continuations of antipsychotic medications following intensive care unit (ICU) discharge, a study has shown.

Pharmacists cut inappropriate antipsychotic use upon discharge

27 Jun 2025

Tocilizumab with or without MTX for acute RA: Does combo work better than mono?

27 Jun 2025 by

Subcutaneous tocilizumab, used either as a monotherapy or in combination with methotrexate (MTX), shows greater efficacy than MTX alone in Chinese patients with active rheumatoid arthritis (RA) who have not adequately responded to conventional synthetic disease-modifying antirheumatic drugs (csDMARDs).

Tocilizumab with or without MTX for acute RA: Does combo work better than mono?

27 Jun 2025

MOSAIC updates: MRI outcomes bolster apremilast role in PsA dactylitis

27 Jun 2025 by

Apremilast, an oral immunomodulating phosphodiesterase-4 inhibitor, reduces inflammation in individual joints and clinical dactylitis as per MRI in patients with psoriatic arthritis (PsA), according to the results of a dynamic contrast-enhanced MRI (DCE-MRI) analysis of the phase IV, open-label MOSAIC study.

MOSAIC updates: MRI outcomes bolster apremilast role in PsA dactylitis

27 Jun 2025

Anifrolumab may enhance quality of life in lupus

27 Jun 2025

Patients with systemic lupus erythematosus (SLE) treated with anifrolumab over 4 years appear to report improvements in health status and quality of life, according to data from the TULIP long-term extension trial (TULIP-LTE).

Anifrolumab may enhance quality of life in lupus

27 Jun 2025

Semaglutide superior to empagliflozin in lowering mortality, CV risks in T2D patients

26 Jun 2025

Treatment with semaglutide may offer some advantage over empagliflozin, with a recent study showing a much lower risk of death and cardiovascular (CV) events among patients with type 2 diabetes (T2D) who received semaglutide.

Semaglutide superior to empagliflozin in lowering mortality, CV risks in T2D patients

26 Jun 2025

Add-on obinutuzumab yields robust treatment benefit in lupus nephritis

26 Jun 2025 by

In a post hoc analysis using the phase III REGENCY study dataset, obinutuzumab on top of standard therapy (ST) demonstrates significant superiority to placebo plus ST across numerous renal response definitions in patients with active lupus nephritis (LN).

Add-on obinutuzumab yields robust treatment benefit in lupus nephritis

26 Jun 2025

Spironolactone prevents renal fibrosis due to hypertension

25 Jun 2025

The use of spironolactone provides protective benefits against hypertension-induced renal fibrosis by promoting autophagy and preventing the activation of NLRP3 inflammasome, according to a study.

Spironolactone prevents renal fibrosis due to hypertension

25 Jun 2025

Adding low-dose aspirin to calcium does not prevent pre-eclampsia in high-risk pregnancies

25 Jun 2025

Treatment with low-dose aspirin, when added to calcium, early in pregnancy does not appear to provide any benefit in terms of reducing the incidence of pre-eclampsia as well as caesarean section or other important neonatal outcomes in high-risk women, according to a study.

Adding low-dose aspirin to calcium does not prevent pre-eclampsia in high-risk pregnancies

25 Jun 2025

Erenumab of no benefit to patients with chronic cluster headache

24 Jun 2025

Calcitonin gene-related peptide (CGRP) receptor blockade with erenumab does not appear to reduce the weekly frequency of cluster headache attacks, as shown in a study from Germany.

Erenumab of no benefit to patients with chronic cluster headache

24 Jun 2025

Real-world data captures risk of major cardiac events with cannabis use

24 Jun 2025 by

Cannabis users are at increased risk of major adverse cardiovascular events (MACE), according to the results of a meta-analysis based on real-world data.

Real-world data captures risk of major cardiac events with cannabis use

24 Jun 2025

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Pharmacists cut inappropriate antipsychotic use upon discharge

Pharmacists cut inappropriate antipsychotic use upon discharge

Tocilizumab with or without MTX for acute RA: Does combo work better than mono?

Tocilizumab with or without MTX for acute RA: Does combo work better than mono?

MOSAIC updates: MRI outcomes bolster apremilast role in PsA dactylitis

MOSAIC updates: MRI outcomes bolster apremilast role in PsA dactylitis

Anifrolumab may enhance quality of life in lupus

Anifrolumab may enhance quality of life in lupus

Semaglutide superior to empagliflozin in lowering mortality, CV risks in T2D patients

Semaglutide superior to empagliflozin in lowering mortality, CV risks in T2D patients

Add-on obinutuzumab yields robust treatment benefit in lupus nephritis

Add-on obinutuzumab yields robust treatment benefit in lupus nephritis

Spironolactone prevents renal fibrosis due to hypertension

Spironolactone prevents renal fibrosis due to hypertension

Adding low-dose aspirin to calcium does not prevent pre-eclampsia in high-risk pregnancies

Adding low-dose aspirin to calcium does not prevent pre-eclampsia in high-risk pregnancies

Erenumab of no benefit to patients with chronic cluster headache

Erenumab of no benefit to patients with chronic cluster headache

Real-world data captures risk of major cardiac events with cannabis use

Real-world data captures risk of major cardiac events with cannabis use