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Pott’s puffy tumor not uncommon in teens with prolonged headache

10 Oct 2023

A recent study recommends having a high index of suspicion for Pott’s puffy tumour (PPT), a rare complication of frontal sinusitis, among adolescents who present with prolonged headache or frontal swelling.

Pott’s puffy tumor not uncommon in teens with prolonged headache

10 Oct 2023

Original New Drug Application Approvals by US FDA (15-30 September 2023)

10 Oct 2023

New drug applications approved by US FDA as of 15-30 September 2023 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (15-30 September 2023)

10 Oct 2023

H pylori a usual finding during endoscopy for other paediatric GI diseases

09 Oct 2023

A common incidental discovery during upper endoscopy for the diagnosis of common paediatric gastrointestinal (GI) diseases is Helicobacter pylori (H pylori) gastritis, a recent study has revealed. However, indications for treatment are not clear and warrant further research.

H pylori a usual finding during endoscopy for other paediatric GI diseases

09 Oct 2023

Renal relapse in childhood-onset lupus nephritis: When? Who’s at risk?

06 Oct 2023 by

A 20-year retrospective study in Hong Kong has shown that renal relapse generally occurs within the first 5 years after diagnosis of childhood-onset lupus nephritis (cLN) in Chinese patients. The risk of renal relapse is higher in those diagnosed at young age, those failing to achieve complete remission (CR) 12 months after induction therapy, and those receiving maintenance therapy other than mycophenolate mofetil (MMF).

Renal relapse in childhood-onset lupus nephritis: When? Who’s at risk?

06 Oct 2023

$Early-life exposure to acid suppressants may up risk of fractures during childhood$

Early-life exposure to acid suppressants may up risk of fractures during childhood

06 Oct 2023

Exposure to acid-suppressive therapy during the first year of life appear to come with a small but significant increase in the risk of fractures, according to a study.

Early-life exposure to acid suppressants may up risk of fractures during childhood

06 Oct 2023

Multistrain probiotics improve survival outcomes in preemies

04 Oct 2023 by

Multistrain probiotics confer significant mortality-reduction benefit in preterm infants, according to the results of a network meta-analysis.

Multistrain probiotics improve survival outcomes in preemies

04 Oct 2023

Increasing BP level in late adolescence ups risk of cardiovascular events

04 Oct 2023

Rising levels of blood pressure (BP), starting at 120/80 mm Hg, during late adolescence contribute to a gradual elevation in the risk of major cardiovascular events, reports a study in Sweden.

Increasing BP level in late adolescence ups risk of cardiovascular events

04 Oct 2023

Long-term prophylaxis reduces attacks, improves QoL in Chinese patients with hereditary angioedema

04 Oct 2023 by

In a prospective study by the University of Hong Kong, long-term prophylaxis (LTP) with garadacimab or lanadelumab reduces attacks and improves quality of life (QoL) in Chinese patients with hereditary angioedema (HAE) who experienced frequent attacks. No adverse events (AEs) were reported.

Long-term prophylaxis reduces attacks, improves QoL in Chinese patients with hereditary angioedema

04 Oct 2023

Dabrafenib-trametinib combo improves response in BRAF V600-mutant paediatric glioma

04 Oct 2023 by

First-line treatment with dabrafenib plus trametinib significantly increased overall response rate (ORR) in paediatric patients with low-grade glioma harbouring BRAF V600 mutations compared with standard chemotherapy, according to a recent study.

Dabrafenib-trametinib combo improves response in BRAF V600-mutant paediatric glioma

04 Oct 2023

Selfhood development tied to adolescent mental health

28 Sep 2023 by

A meta-analysis found evidence associating selfhood development with adolescent mental health.

Selfhood development tied to adolescent mental health

28 Sep 2023

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Pott’s puffy tumor not uncommon in teens with prolonged headache

Pott’s puffy tumor not uncommon in teens with prolonged headache

Original New Drug Application Approvals by US FDA (15-30 September 2023)

Original New Drug Application Approvals by US FDA (15-30 September 2023)

H pylori a usual finding during endoscopy for other paediatric GI diseases

H pylori a usual finding during endoscopy for other paediatric GI diseases

Renal relapse in childhood-onset lupus nephritis: When? Who’s at risk?

Renal relapse in childhood-onset lupus nephritis: When? Who’s at risk?

Early-life exposure to acid suppressants may up risk of fractures during childhood

Early-life exposure to acid suppressants may up risk of fractures during childhood

Multistrain probiotics improve survival outcomes in preemies

Multistrain probiotics improve survival outcomes in preemies

Increasing BP level in late adolescence ups risk of cardiovascular events

Increasing BP level in late adolescence ups risk of cardiovascular events

Long-term prophylaxis reduces attacks, improves QoL in Chinese patients with hereditary angioedema

Long-term prophylaxis reduces attacks, improves QoL in Chinese patients with hereditary angioedema

Dabrafenib-trametinib combo improves response in BRAF V600-mutant paediatric glioma

Dabrafenib-trametinib combo improves response in BRAF V600-mutant paediatric glioma

Selfhood development tied to adolescent mental health

Selfhood development tied to adolescent mental health