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Aficamten retains upper hand over metoprolol for oHCM in subanalysis
14 Sep 2026
byAudrey Abella
Results from a subanalysis of the MAPLE-HCM* trial presented at ESC 2026 continue to support the superiority of aficamten over metoprolol in patients with symptomatic obstructive hypertrophic cardiomyopathy (oHCM) irrespective of beta-blocker (BB) use at screening and prior standard-of-care (SoC) status.
14 Sep 2026

Uromodulin levels do not predict hypertension
11 Sep 2026
byStephen Padilla
Uromodulin, as a protein and genetic biomarker, is not a reliable predictor of hypertension or hypertension-related outcomes, reveals a study. However, it may have potential use in the prediction of other cardiovascular outcomes.
11 Sep 2026

SHASTA trials boost plozasiran potential in severe hypertriglyceridaemia
10 Sep 2026
byAudrey Abella
In the SHASTA-3 and SHASTA-4 trials, quarterly administration of plozasiran reduced triglyceride (TG) levels and acute pancreatitis (AP) events in individuals with severe hypertriglyceridaemia (sHTG; TG ≥500 mg/dL).
10 Sep 2026





