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Z-drug exposure during early pregnancy not a risk factor for congenital malformations

14 Jan 2026

The use of nonbenzodiazepine sedative hypnotics (Z-drugs) for sleep dysregulation during the first trimester of pregnancy does not appear to contribute to a meaningful increase in the risk of congenital malformations overall, as shown in a study.

Z-drug exposure during early pregnancy not a risk factor for congenital malformations

14 Jan 2026

CHD subtypes linked to increased risk of low Apgar scores in newborns

14 Jan 2026 by

According to a study, several congenital heart defect (CHD) subtypes are associated with an elevated risk of low Apgar scores at 5 mins after birth in newborns.

CHD subtypes linked to increased risk of low Apgar scores in newborns

14 Jan 2026

Omega-3 fatty acid supplementation does nothing for youths with depression

13 Jan 2026

In the treatment of children and adolescents with major depressive disorder (MDD), adjunctive supplementation with omega-3 fatty acid does not appear to significantly improve outcomes compared with placebo, according to study.

Omega-3 fatty acid supplementation does nothing for youths with depression

13 Jan 2026

Rapid hair regrowth in a patient with alopecia universalis treated with a JAK3/TEC family kinase inhibitor

13 Jan 2026 by

A 12-year-old boy presented with longstanding alopecia universalis (AU) in March 2024, with complete loss of scalp hair corresponding to a Severity of Alopecia Tool (SALT) score of 100, as well as loss of all eyebrows, eyelashes, and body hair. Responses to previous treatments were suboptimal. In September 2024, the patient (SALT 50) was switched to ritlecitinib 50 mg QD as it had become available in Hong Kong through a medication access programme. By February 2025, the patient’s SALT score had improved to 0–10 (complete scalp hair regrowth), with complete regrowth of eyebrows and eyelashes.

Rapid hair regrowth in a patient with alopecia universalis treated with a JAK3/TEC family kinase inhibitor

13 Jan 2026

Original-New-Drug-Application-Approvals-by-US-FDA--1-15-December-2025

06 Jan 2026

New drug applications approved by US FDA as of 1-15 December 2025 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original-New-Drug-Application-Approvals-by-US-FDA--1-15-December-2025

06 Jan 2026

Original New Drug Application Approvals by US FDA (16-31 December 2025)

06 Jan 2026

New drug applications approved by US FDA as of 16-31 December 2025 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (16-31 December 2025)

06 Jan 2026

Adequate sleep helps prevent obesity in boys

05 Jan 2026

A recent study suggests interventions for children to help them achieve their recommended sleep duration for weekdays and weekends and thus reduce abdominal and total adiposity, particularly in boys.

Adequate sleep helps prevent obesity in boys

05 Jan 2026

Follow-up care a must for late effects in childhood cancer survivors

05 Jan 2026 by

Timely screening is needed to enhance early detection of metabolic health, bone health, and hearing impairment among childhood cancer survivors treated in Singapore, suggests a recent study. Adoption of an exposure-based approach to proactively screen for late effects can reduce biopsychosocial impacts.

Follow-up care a must for late effects in childhood cancer survivors

05 Jan 2026

Maternal prepregnancy BMI predicts cardiometabolic outcomes in offspring

05 Jan 2026

High maternal BMI prior to pregnancy appears to contribute to a BMI increase in their offspring during childhood, reveals a study. Moreover, preterm children are more likely to develop hypertension than their term counterparts.

Maternal prepregnancy BMI predicts cardiometabolic outcomes in offspring

05 Jan 2026

Childhood maltreatment increases schizophrenia risk 5-fold

02 Jan 2026 by

Childhood maltreatment increases the risk of schizophrenia by five-fold, attention deficit hyperactivity disorder (ADHD) by 10-fold, and major depressive disorder (MDD) by nearly two-fold. It also leaves lasting genetic markers linked to neurodegenerative conditions, including Alzheimer’s disease and Parkinson’s disease, a Mendelian randomization study has shown.

Childhood maltreatment increases schizophrenia risk 5-fold

02 Jan 2026

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Z-drug exposure during early pregnancy not a risk factor for congenital malformations

Z-drug exposure during early pregnancy not a risk factor for congenital malformations

CHD subtypes linked to increased risk of low Apgar scores in newborns

CHD subtypes linked to increased risk of low Apgar scores in newborns

Omega-3 fatty acid supplementation does nothing for youths with depression

Omega-3 fatty acid supplementation does nothing for youths with depression

Rapid hair regrowth in a patient with alopecia universalis treated with a JAK3/TEC family kinase inhibitor

Rapid hair regrowth in a patient with alopecia universalis treated with a JAK3/TEC family kinase inhibitor

Original-New-Drug-Application-Approvals-by-US-FDA--1-15-December-2025

Original-New-Drug-Application-Approvals-by-US-FDA--1-15-December-2025

Original New Drug Application Approvals by US FDA (16-31 December 2025)

Original New Drug Application Approvals by US FDA (16-31 December 2025)

Adequate sleep helps prevent obesity in boys

Adequate sleep helps prevent obesity in boys

Follow-up care a must for late effects in childhood cancer survivors

Follow-up care a must for late effects in childhood cancer survivors

Maternal prepregnancy BMI predicts cardiometabolic outcomes in offspring

Maternal prepregnancy BMI predicts cardiometabolic outcomes in offspring

Childhood maltreatment increases schizophrenia risk 5-fold

Childhood maltreatment increases schizophrenia risk 5-fold