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Fenofibrate beneficial in PBC patients with insufficient response to ursodeoxycholic acid

In patients with primary biliary cholangitis (PBC) with insufficient response to ursodeoxycholic acid, outcomes appear to improve following treatment with fenofibrate, as shown in a single-centre retrospective cohort study.

Fenofibrate beneficial in PBC patients with insufficient response to ursodeoxycholic acid

5 hours ago

Malignant disease may re-emerge following SOT among cancer survivors

21 Mar 2026

Solid organ transplant (SOT) recipients with a history of cancer are at increased risk of post-transplant cancer, especially the same type of cancer, according to a study.

Malignant disease may re-emerge following SOT among cancer survivors

21 Mar 2026

HK study: START-FIT strategy using STRIDE regimen promising in HCC

17 Mar 2026 by

Sequential transarterial chemoembolization, stereotactic body radiotherapy, and immunotherapy (START-FIT) using the STRIDE regimen of single-dose tremelimumab plus regular-interval durvalumab offers promising efficacy and is well tolerated in patients with locally advanced, unresectable hepatocellular carcinoma (HCC), a single-arm, multicentre, phase II study in Hong Kong has shown.

HK study: START-FIT strategy using STRIDE regimen promising in HCC

17 Mar 2026

DTG/3TC tied to lower steatotic liver disease rates in PLWH

17 Mar 2026 by

Switching to dolutegravir/lamivudine (DTG/3TC) was associated with a significantly lower rate of steatotic liver disease (SLD) compared with bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) among people living with HIV (PLWH), according to a subgroup analysis of the PASO DOBLE trial presented at CROI 2026.

DTG/3TC tied to lower steatotic liver disease rates in PLWH

17 Mar 2026

Novel drug safe, efficacious in patients with HDV-related advanced liver disease

10 Mar 2026

Treatment with REP 2139-Mg (REP), a nucleic acid polymer, demonstrates efficacy and an acceptable safety profile among patients with hepatitis D virus (HDV) and advanced chronic liver disease (CLD), reports a recent study.

Novel drug safe, efficacious in patients with HDV-related advanced liver disease

10 Mar 2026

Pig-to-human liver transplantation promises cure for hepatic diseases

10 Mar 2026 by

A genetically engineered pig liver has been successfully transplanted in a living human, according to a recent study, noting the challenge posed by postoperative xenotransplantation-associated thrombotic microangiopathy (xTMA) to long-term success.

Pig-to-human liver transplantation promises cure for hepatic diseases

10 Mar 2026

Obesity in parents linked to MASLD risk in adult offspring

07 Mar 2026

Excess parental adiposity prior to pregnancy is associated with increased likelihood of metabolic dysfunction-associated steatotic liver disease (MASLD) development in offspring as adults, as mediated by higher BMI throughout childhood, according to a study.

Obesity in parents linked to MASLD risk in adult offspring

07 Mar 2026

Alcohol drinking even in small amount raises risk of steatotic liver disease

05 Mar 2026

Even light or moderate consumption of alcohol can still increase the risk of steatotic liver disease (SLD) and its metabolic dysfunction-associated subtype (MASLD), suggests a study. Furthermore, a gut microbial score based on alcohol-associated species predicts a higher disease risk.

Alcohol drinking even in small amount raises risk of steatotic liver disease

05 Mar 2026

Immune-related AEs linked to better outcomes in HCC patients

02 Mar 2026

Patients with hepatocellular carcinoma (HCC) who develop immune-related adverse events (irAEs) following treatment with an immune checkpoint inhibitor (ICI) tend to have more favourable clinical outcomes, including better progression free survival (PFS) and objective response rate (ORR), reports a recent study.

Immune-related AEs linked to better outcomes in HCC patients

02 Mar 2026

Annual increase in HCC deaths higher among rural vs urban residents

01 Mar 2026

Rural area residents have seen greater increases in hepatocellular carcinoma (HCC) deaths each year than those living in urban areas, reveals a study.

Annual increase in HCC deaths higher among rural vs urban residents

01 Mar 2026

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Fenofibrate beneficial in PBC patients with insufficient response to ursodeoxycholic acid

Fenofibrate beneficial in PBC patients with insufficient response to ursodeoxycholic acid

Malignant disease may re-emerge following SOT among cancer survivors

Malignant disease may re-emerge following SOT among cancer survivors

HK study: START-FIT strategy using STRIDE regimen promising in HCC

HK study: START-FIT strategy using STRIDE regimen promising in HCC

DTG/3TC tied to lower steatotic liver disease rates in PLWH

DTG/3TC tied to lower steatotic liver disease rates in PLWH

Novel drug safe, efficacious in patients with HDV-related advanced liver disease

Novel drug safe, efficacious in patients with HDV-related advanced liver disease

Pig-to-human liver transplantation promises cure for hepatic diseases

Pig-to-human liver transplantation promises cure for hepatic diseases

Obesity in parents linked to MASLD risk in adult offspring

Obesity in parents linked to MASLD risk in adult offspring

Alcohol drinking even in small amount raises risk of steatotic liver disease

Alcohol drinking even in small amount raises risk of steatotic liver disease

Immune-related AEs linked to better outcomes in HCC patients

Immune-related AEs linked to better outcomes in HCC patients

Annual increase in HCC deaths higher among rural vs urban residents

Annual increase in HCC deaths higher among rural vs urban residents