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Esketamine monotherapy shows robust, rapid efficacy as treatment for TRD

Intranasal esketamine, administered at two fixed doses as monotherapy for treatment-resistant depression (TRD), has demonstrated robust and rapid efficacy in a phase IV double-blind, placebo-controlled randomized trial.

Esketamine monotherapy shows robust, rapid efficacy as treatment for TRD

6 hours ago

Hepatic steatosis linked to lower mortality in CLD patients

17 hours ago

The presence of substantial hepatic steatosis estimated by controlled attenuated parameter (CAP) score among patients who underwent vibration-controlled transient elastography (VCTE) appears to reduce the risk of all-cause mortality and decompensation, particularly in those with metabolic dysfunction-associated steatotic liver disease (MASLD), reports a study.

Hepatic steatosis linked to lower mortality in CLD patients

17 hours ago

Oral frailty tied to worse physical, mental health in older adults

18 hours ago by

Oral frailty can lead to negative outcomes in older adults, including poorer physical health and reduced cognition, according to a study. Early identification can help prevent these harmful consequences.

Oral frailty tied to worse physical, mental health in older adults

18 hours ago

Ustekinumab improves outcomes in UC patients

19 hours ago

Treatment with ustekinumab can help patients with ulcerative colitis (UC) achieve clinical and endoscopic outcomes of importance after 12 months, results of a real-world study have shown.

Ustekinumab improves outcomes in UC patients

19 hours ago

RA onset delayed through 4 years with 1-year abatacept treatment in at-risk individuals

a day ago by

A 12-month therapeutic intervention with self-administered abatacept can delay the onset of rheumatoid arthritis (RA) in at-risk individuals for up to 4 years, according to results from the ALTO follow-up study presented at EULAR 2025.

RA onset delayed through 4 years with 1-year abatacept treatment in at-risk individuals

a day ago

BMI mediates link between diabetes, food insecurity

a day ago

A recent study has shown the significant role that BMI plays in the relationship between food insecurity and diabetes.

BMI mediates link between diabetes, food insecurity

a day ago

Exercise prevents death in diabetes patients with MI

a day ago by

Regularly engaging in any physical activity (PA) can help reduce the risk of death in patients with diabetes and myocardial infarction (MI), suggests a study presented at ADA 2025.

Exercise prevents death in diabetes patients with MI

a day ago

Initial vision, infiltrate size predict outcomes in microbial keratitis

a day ago

Several factors contribute to the risk for worse 90-day best-corrected visual acuity (BCVA) in patients with microbial keratitis (MK), and these include initial vision, longer time until presentation, and larger infiltrate size, reports a study.

Initial vision, infiltrate size predict outcomes in microbial keratitis

a day ago

Tirzepatide improves cardiometabolic markers in Chinese adults

a day ago

Early weight loss associated with the use of tirzepatide may significantly improve cardiometabolic health, particularly in adults achieving a normal BMI by week 52, according to a China study.

Tirzepatide improves cardiometabolic markers in Chinese adults

a day ago

Cannabis use doubles the risk of dying from heart disease

a day ago by

Cannabis use increases the risk of major adverse cardiovascular events (MACE), as shown in a robust meta-analysis, raising serious questions about the assumptions that cannabis use poses little cardiovascular (CV) risk among users.

Cannabis use doubles the risk of dying from heart disease

a day ago

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Esketamine monotherapy shows robust, rapid efficacy as treatment for TRD

Esketamine monotherapy shows robust, rapid efficacy as treatment for TRD

Hepatic steatosis linked to lower mortality in CLD patients

Hepatic steatosis linked to lower mortality in CLD patients

Oral frailty tied to worse physical, mental health in older adults

Oral frailty tied to worse physical, mental health in older adults

Ustekinumab improves outcomes in UC patients

Ustekinumab improves outcomes in UC patients

RA onset delayed through 4 years with 1-year abatacept treatment in at-risk individuals

RA onset delayed through 4 years with 1-year abatacept treatment in at-risk individuals

BMI mediates link between diabetes, food insecurity

BMI mediates link between diabetes, food insecurity

Exercise prevents death in diabetes patients with MI

Exercise prevents death in diabetes patients with MI

Initial vision, infiltrate size predict outcomes in microbial keratitis

Initial vision, infiltrate size predict outcomes in microbial keratitis

Tirzepatide improves cardiometabolic markers in Chinese adults

Tirzepatide improves cardiometabolic markers in Chinese adults

Cannabis use doubles the risk of dying from heart disease

Cannabis use doubles the risk of dying from heart disease