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Is sildenafil neuroprotective?

14 Jul 2025 by

A systematic review and meta-analysis conducted by researchers from Singapore demonstrates an association between treatment with sildenafil, a phosphodiesterase-5 (PDE5) inhibitor, and the risk of Alzheimer's disease (AD).

Is sildenafil neuroprotective?

14 Jul 2025

CGRP-targeted therapies herald a new era in migraine management

14 Jul 2025 by

Calcitonin gene–related peptide (CGRP)–targeted therapies are likely to become a mainstay of migraine headache treatment in the coming decades as they have demonstrated efficacy for acute and preventive treatment, according to Dr Yi-Jing Zhao of Mount Elizabeth Hospital, Singapore, who spoke at AIM 2025.

CGRP-targeted therapies herald a new era in migraine management

14 Jul 2025

Ambroxol safe but fails to improve cognition in Parkinson’s disease dementia

11 Jul 2025

Treatment with ambroxol in patients with Parkinson’s disease dementia (PDD) is safe and well tolerated but falls short of improving cognition, according to a single-centre phase II study.

Ambroxol safe but fails to improve cognition in Parkinson’s disease dementia

11 Jul 2025

Fibromyalgia linked to lower sexual desire in women

08 Jul 2025

Sexual desire is reduced in women with fibromyalgia, driven primarily by age, time since diagnosis, and depressive symptoms, according to a study.

Fibromyalgia linked to lower sexual desire in women

08 Jul 2025

More cognitive issues, fewer heart problems after COVID-19 vs flu hospitalization in Asians

04 Jul 2025 by

Individuals hospitalized for COVID-19 vs seasonal influenza face a greater risk of cognitive impairment and fatigue but a lower risk of cardiac disorders as long-term consequences of infection, according to a retrospective population-based cohort study in Singapore.

More cognitive issues, fewer heart problems after COVID-19 vs flu hospitalization in Asians

04 Jul 2025

Diagnosing transient loss of consciousness: Approach to a common clinical conundrum

04 Jul 2025 by

Over 90 percent of transient loss of consciousness (TLOC) presentations are due to syncope, seizure or psychogenic causes, but up to 30 percent of them are misdiagnosed initially due to significant overlap in manifestations, according to Dr Charlie Chan of the Prince of Wales Hospital, who shared tips on diagnosis at AIM 2025.

Diagnosing transient loss of consciousness: Approach to a common clinical conundrum

04 Jul 2025

Blood-based biomarkers may aid earlier diagnosis of Alzheimer’s disease

01 Jul 2025 by

Blood-based biomarkers (BBBs) may potentially aid earlier detection of Alzheimer’s disease (AD) following a recent revision of diagnostic criteria supporting core biomarker–based diagnosis. Initial local experience with lecanemab, a disease-modifying therapy (DMT) for patients with mild cognitive impairment or mild dementia due to AD, was shared at Advances in Medicine (AIM) 2025.

Blood-based biomarkers may aid earlier diagnosis of Alzheimer’s disease

01 Jul 2025

Sugary, artificially sweetened beverages pose no risk of dementia in older adults

26 Jun 2025

Increased intake of sugar-sweetened beverages (SSB) or artificially sweetened beverages (ASB) does not appear to contribute to the risk of dementia in older adults, according to a study.

Sugary, artificially sweetened beverages pose no risk of dementia in older adults

26 Jun 2025

Erenumab of no benefit to patients with chronic cluster headache

24 Jun 2025

Calcitonin gene-related peptide (CGRP) receptor blockade with erenumab does not appear to reduce the weekly frequency of cluster headache attacks, as shown in a study from Germany.

Erenumab of no benefit to patients with chronic cluster headache

24 Jun 2025

Wearable electroencephalograph device useful for detecting absence seizures

22 Jun 2025 by

A wearable electroencephalograph (EEG) device that leverages artificial intelligence allows for precise, 12-to-24-h home monitoring of absence seizures, enabling rapid and tailored adjustments to antiseizure medication (ASM) and eliminating the need for further hospital admissions, as shown in an exploratory study.

Wearable electroencephalograph device useful for detecting absence seizures

22 Jun 2025

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Is sildenafil neuroprotective?

Is sildenafil neuroprotective?

CGRP-targeted therapies herald a new era in migraine management

CGRP-targeted therapies herald a new era in migraine management

Ambroxol safe but fails to improve cognition in Parkinson’s disease dementia

Ambroxol safe but fails to improve cognition in Parkinson’s disease dementia

Fibromyalgia linked to lower sexual desire in women

Fibromyalgia linked to lower sexual desire in women

More cognitive issues, fewer heart problems after COVID-19 vs flu hospitalization in Asians

More cognitive issues, fewer heart problems after COVID-19 vs flu hospitalization in Asians

Diagnosing transient loss of consciousness: Approach to a common clinical conundrum

Diagnosing transient loss of consciousness: Approach to a common clinical conundrum

Blood-based biomarkers may aid earlier diagnosis of Alzheimer’s disease

Blood-based biomarkers may aid earlier diagnosis of Alzheimer’s disease

Sugary, artificially sweetened beverages pose no risk of dementia in older adults

Sugary, artificially sweetened beverages pose no risk of dementia in older adults

Erenumab of no benefit to patients with chronic cluster headache

Erenumab of no benefit to patients with chronic cluster headache

Wearable electroencephalograph device useful for detecting absence seizures

Wearable electroencephalograph device useful for detecting absence seizures