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Ustekinumab vs vedolizumab for older IBD patients: MACE not different, but mortality lower
In the real-world treatment of older adults with inflammatory bowel disease (IBD), the cardiovascular safety of ustekinumab is similar to that of vedolizumab, with no significant difference in the risk of major adverse cardiovascular events (MACE). However, ustekinumab is associated with a reduced risk of all-cause mortality.
Ustekinumab vs vedolizumab for older IBD patients: MACE not different, but mortality lower
28 Feb 2025
Severe maternal morbidity up by fourfold in presence of CRC
Pregnant women with colorectal cancer (CRC) face a considerably increased likelihood of severe maternal morbidity, including disseminated intravascular coagulation, acute respiratory distress syndrome, and hysterectomy, among others, according to a study.
Severe maternal morbidity up by fourfold in presence of CRC
27 Feb 2025
Experts look beyond BMI to diagnose obesity
Experts have proposed a subtle approach to diagnosing obesity that shifts the focus from BMI alone. Instead, they urged using other body fat measures such as waist circumference or direct fat mass measurement and signs and symptoms of ill health to confirm excess body fat.
Experts look beyond BMI to diagnose obesity
24 Feb 2025
Long-term colchicine use helps prevent stroke, cardiac events
Treatment with colchicine appears to lower the risk of stroke and major adverse cardiovascular events (MACE) when used for longer duration, according to a study presented at ISC 2025. This beneficial effect, however, is not observed among patients with shorter follow-up duration.