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Obesity, prediabetes up risk of diabetes in statin-treated PWH
People living with HIV (PWH) on statin therapy who have certain metabolic risk factors, such as obesity and prediabetes, are at greater risk of developing diabetes mellitus (DM), reports a study. This association is also present in those treated with placebo.
Obesity, prediabetes up risk of diabetes in statin-treated PWH
29 Oct 2024
Happiness is key to a healthy heart
An analysis using the UK Biobank dataset shows a robust inverse association between well-being and risk of cardiovascular diseases (CVDs), underpinning the protective effect of higher well-being on the four major CVDs evaluated: coronary heart disease, MI, heart failure (HF), and stroke.
Happiness is key to a healthy heart
29 Oct 2024
FASN inhibitor for MASH with fibrosis gets a pass to phase III
The oral fatty acid synthase (FASN) inhibitor denifanstat appears to produce meaningful improvements in metabolic dysfunction-associated steatohepatitis (MASH) and stage 2–3 fibrosis, as shown in the results of a phase IIb trial.
FASN inhibitor for MASH with fibrosis gets a pass to phase III
28 Oct 2024
Insulin resistance linked to future hypertension in normotensive salt-sensitive individuals
A 10-year study has found the association of salt sensitivity with insulin resistance and endothelial dysfunction in the offspring of hypertensive salt-sensitive parents, making them susceptible to developing hypertension.
