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Is it safe to use pyrazinamide in older patients with TB?
Adding pyrazinamide (PZA) to the initial tuberculosis (TB) treatment in older patients may lead to an increase in the incidence of adverse events (AEs), particularly allergic reactions, but not in-hospital mortality, length of hospital stay, or hepatotoxicity, reports a study, which used data from the Japanese Diagnosis Procedure Combination inpatient database.
Is it safe to use pyrazinamide in older patients with TB?
01 Oct 2024
Cytisine on par with nortriptyline for smoking cessation
Treatment with cytisine shows comparable efficacy to that of nortriptyline for smoking cessation at 1 year, according to a study. In addition, adverse events for both medications are few and well-tolerated.
Cytisine on par with nortriptyline for smoking cessation
30 Sep 2024
Benralizumab offers sustained remission in severe eosinophilic asthma
Treatment with benralizumab (BRZ) results in sustained remission in patients with severe eosinophilic asthma (SEA), particularly those with comorbid chronic rhinosinusitis with nasal polyps (CRSwNP) and reversible airflow limitation, reports a study.
Benralizumab offers sustained remission in severe eosinophilic asthma
30 Sep 2024
Large UK study underpins role of COVID-19 vax in mental illness
In a cohort study of over 18 million individuals with up to 2 years of follow-up, the incidences of most mental illnesses were markedly elevated following COVID-19 diagnosis compared with before or without COVID-19, particularly among the unvaccinated and before COVID-19 vaccines became available.
Large UK study underpins role of COVID-19 vax in mental illness
27 Sep 2024
Many Singaporeans suffer from undiagnosed, undertreated allergic rhinitis
A substantial number of allergic rhinitis (AR) cases in Singapore, particularly those with more severe symptoms, remain undiagnosed or receive inadequate treatment. This contributes to a hidden but significant burden of AR in the population, as shown in a study.
Many Singaporeans suffer from undiagnosed, undertreated allergic rhinitis
26 Sep 2024
Chronic bronchitis symptoms hint at benefits of mepolizumab in COPD with T2 inflammation
The presence of chronic bronchitis symptoms in COPD with T2 inflammation drives a more pronounced and significant benefit from mepolizumab in terms of reducing CAT scores, as shown in a post hoc analysis pooling data from two phase III trials — METREX and METREO
Chronic bronchitis symptoms hint at benefits of mepolizumab in COPD with T2 inflammation
25 Sep 2024
Long-term benefits with molnupiravir modest at best in COVID-19 treatment
The antiviral molnupiravir confers continued but modest benefits in terms of reducing COVID-19–related symptoms up to 6 months after the index infection in a vaccinated population, according to a secondary analysis of the PANORAMIC trial.
Long-term benefits with molnupiravir modest at best in COVID-19 treatment
24 Sep 2024
Women with asthma more likely to need fertility treatment
Women with asthma have a higher likelihood of necessitating fertility treatment, according to a Danish nationwide historical cohort study presented at ERS 2024.