News &amp; Updates

For individuals who completed treatment for pulmonary tuberculosis (TB), vaccination with H56:IC31 does not appear to reduce the risk of disease recurrence, according to a phase 2b trial.

H56:IC31 vaccine of no help against TB recurrence

Original New Drug Application Approvals by US FDA (16-28 February 2025)

New drug applications approved by US FDA as of 16-28 February 2025 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (16-28 February 2025)

$Upadacitinib for refractory CD safe, effective in real-world use$

Upadacitinib for refractory CD safe, effective in real-world use

In a real-world cohort of patients with highly refractory Crohn’s disease (CD), upadacitinib treatment prompted clinical response in most and steroid-free clinical remission in half, while having an acceptable safety profile.

Upadacitinib for refractory CD safe, effective in real-world use

SG sees drop in paediatric pneumococcal disease burden

13 Mar 2025 by

The introduction of pneumococcal conjugate vaccines (PCV) into Singapore's National Childhood Immunisation Schedule (NCIS) has reduced the incidence of invasive pneumococcal disease (IPD) in children by nearly a third, as reported in a study.

SG sees drop in paediatric pneumococcal disease burden

Young adults unaware of male HPV infection, vaccine benefits

13 Mar 2025 by

Awareness about human papillomavirus (HPV) infection in males and the benefits of vaccination on both genders is low among young adults, reveals a Singapore study.

Young adults unaware of male HPV infection, vaccine benefits

High-dose multivitamins, multiminerals offer no cardioprotection in chronic coronary disease

For patients with chronic coronary disease, diabetes, and a previous myocardial infarction (MI), treatment with high-dose oral multivitamins and multiminerals (OMVM) alone or in conjunction with edetate disodium chelation therapy does not appear to reduce the incidence of major adverse cardiovascular events, as reported in a study.

High-dose multivitamins, multiminerals offer no cardioprotection in chronic coronary disease

Nebivolol lowers risk of ED occurrence, progression

The use of nebivolol, compared with metoprolol, results in a significant reduction in the risk of erectile dysfunction (ED) occurrence or progression, regardless of whether the patient had ED or not, a recent study has shown.

Nebivolol lowers risk of ED occurrence, progression

MVM supplementation may improve mood, lower loneliness in older adults

12 Mar 2025 by

Twelve weeks of multivitamin-mineral (MVM) supplementation increases friendliness and reduces perceived stress reactivity and emotional loneliness in older adults, a study has shown.

MVM supplementation may improve mood, lower loneliness in older adults

Iron supplements enhance postural control in young women with anaemia

Oral iron supplementation for 8 weeks results in significant improvements in postural control in young women with iron-deficiency anaemia (IDA).

Iron supplements enhance postural control in young women with anaemia

Drospirenone safer than levonorgestrel when co-administered with psychotropics

For women using contraceptives while on psychotropic drugs, the risk of adverse events appears to be lower with drospirenone than with levonorgestrel, whereas contraceptive failure is uncommon across progestins, according to a real-world study.

Drospirenone safer than levonorgestrel when co-administered with psychotropics