News & Updates

NIPS regimen improves OS in gastric cancer with peritoneal metastasis

12 Mar 2025 by

Among patients with gastric cancer and peritoneal metastasis, treatment with neoadjuvant intraperitoneal–systemic (NIPS) regimen, which consists of intraperitoneal (IP) and intravenous (IV) paclitaxel plus S-1, significantly improved overall survival (OS) compared with IV paclitaxel plus S-1 only (PS regimen), according to the DRAGON-01 trial presented at ASCO GI 2025.

NIPS regimen improves OS in gastric cancer with peritoneal metastasis

12 Mar 2025

HPV vaccines useful for managing actinic keratosis

11 Mar 2025

Standard α-HPV vaccination appears to reduce the burden of actinic keratosis (AK) in individuals with multiple lesions, according to the VAXAK trial.

HPV vaccines useful for managing actinic keratosis

11 Mar 2025

Xanomeline/trospium improves cognition in acute schizophrenia patients with impairment

11 Mar 2025

The use of xanomeline/trospium chloride brings significant cognitive improvements to acute schizophrenia patients with prespecified impairments compared with placebo, a study has shown.

Xanomeline/trospium improves cognition in acute schizophrenia patients with impairment

11 Mar 2025

Ondansetron plus SRI eases OCD severity

11 Mar 2025

Treatment with high-dose ondansetron shows no effect on sensory phenomena (SP) in patients with obsessive-compulsive disorder (OCD), according to a study.

Ondansetron plus SRI eases OCD severity

11 Mar 2025

Radiotherapy plus short-course ADT confers survival benefit in oligometastatic prostate cancer

11 Mar 2025

In patients with oligometastatic hormone-sensitive prostate cancer, the combination of stereotactic body radiotherapy (SBRT) plus a short course of androgen deprivation therapy (ADT) appears to improve progression-free survival (PFS), according to the phase II RADIOSA trial.

Radiotherapy plus short-course ADT confers survival benefit in oligometastatic prostate cancer

11 Mar 2025

Japanese adults with obesity lose weight with once-weekly tirzepatide

10 Mar 2025

Taking tirzepatide once a week appears to result in clinically meaningful reductions in body weight for Japanese adults with obesity, according to the results of the phase III multicentre SURMOUNT-J trial

Japanese adults with obesity lose weight with once-weekly tirzepatide

10 Mar 2025

Allergy history, previous exposure predict oxaliplatin hypersensitivity reactions

10 Mar 2025

A history of allergy, previous oxaliplatin exposure, and chemotherapy regimens are associated with a higher risk of oxaliplatin hypersensitivity reactions in patients with colorectal cancer, reveals a study.

Allergy history, previous exposure predict oxaliplatin hypersensitivity reactions

10 Mar 2025

Original New Drug Application Approvals by US FDA (1-15 February 2025)

10 Mar 2025

New drug applications approved by US FDA as of 1-15 February 2025 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (1-15 February 2025)

10 Mar 2025

Adjuvant nivolumab delivers in muscle-invasive bladder cancer

09 Mar 2025 by

Adjuvant nivolumab appears to improve survival outcomes in patients with muscle-invasive bladder cancer (MIBC) who have undergone radical surgery, regardless of prior exposure to neoadjuvant chemotherapy, according to additional data from the phase III CheckMate 274 trial.

Adjuvant nivolumab delivers in muscle-invasive bladder cancer

09 Mar 2025

Tetracycline trumps macrolide in MRMP pneumonia

09 Mar 2025

Tetracycline demonstrates superior clinical efficacy to that of macrolide in children with macrolide-resistant Mycoplasma pneumoniae (MRMP) pneumonia, a study has shown.

Tetracycline trumps macrolide in MRMP pneumonia

09 Mar 2025

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NIPS regimen improves OS in gastric cancer with peritoneal metastasis

NIPS regimen improves OS in gastric cancer with peritoneal metastasis

HPV vaccines useful for managing actinic keratosis

HPV vaccines useful for managing actinic keratosis

Xanomeline/trospium improves cognition in acute schizophrenia patients with impairment

Xanomeline/trospium improves cognition in acute schizophrenia patients with impairment

Ondansetron plus SRI eases OCD severity

Ondansetron plus SRI eases OCD severity

Radiotherapy plus short-course ADT confers survival benefit in oligometastatic prostate cancer

Radiotherapy plus short-course ADT confers survival benefit in oligometastatic prostate cancer

Japanese adults with obesity lose weight with once-weekly tirzepatide

Japanese adults with obesity lose weight with once-weekly tirzepatide

Allergy history, previous exposure predict oxaliplatin hypersensitivity reactions

Allergy history, previous exposure predict oxaliplatin hypersensitivity reactions

Original New Drug Application Approvals by US FDA (1-15 February 2025)

Original New Drug Application Approvals by US FDA (1-15 February 2025)

Adjuvant nivolumab delivers in muscle-invasive bladder cancer

Adjuvant nivolumab delivers in muscle-invasive bladder cancer

Tetracycline trumps macrolide in MRMP pneumonia

Tetracycline trumps macrolide in MRMP pneumonia