News &amp; Updates

An elevated matrix metalloproteinase-9 (MMP-9) appears to cause lung function decline and the development of chronic obstructive pulmonary disease (COPD), suggests a study.

MMP-9 tied to faster lung function decline, COPD development

SARS-CoV-2 reinfection ups paediatric long COVID risk

12 Dec 2025 by

Findings from the retrospective RECOVER-EHR* study show an increased risk of post-acute sequelae of SARS-CoV-2 infection (PASC), also known as long COVID, in children and adolescents after a SARS-CoV-2 reinfection.

SARS-CoV-2 reinfection ups paediatric long COVID risk

12 Dec 2025

Achieving very good PR with lorlatinib and managing AEs in an ALK-positive NSCLC patient with high tumour burden

12 Dec 2025 by

A 60-year-old female homemaker, never-smoker and never-drinker, with good past health, presented in March 2024 with persistent cough and progressively worsening shortness of breath of 3 weeks following COVID-19 infection. Physical examination revealed an enlarged left supraclavicular lymph node (LN) of approximately 2.5 cm. Chest X-ray (CXR) showed a shadow in the left upper lobe (LUL) of the lung.

Achieving very good PR with lorlatinib and managing AEs in an ALK-positive NSCLC patient with high tumour burden

Doxycycline shows potential schizophrenia-lowering benefit

Psychiatric patients exposed to doxycycline appear to have a reduced risk of schizophrenia, according to a study.

Doxycycline shows potential schizophrenia-lowering benefit

Sleep apnoea may pose increased Parkinson’s disease risk

People with obstructive sleep apnoea seem predisposed to later development of Parkinson’s disease, but this risk can be mitigated by early treatment with continuous positive airway pressure, as reported in a study.

Sleep apnoea may pose increased Parkinson’s disease risk

Continuous use of TNFi on the rise in pregnant women

A trend toward increased continuous use of tumour necrosis factor inhibitors has been observed throughout gestation, which suggests growing confidence in the safety and effectiveness of this medication during pregnancy, reveals a study.

Continuous use of TNFi on the rise in pregnant women

CVD tops disease burden, death cause worldwide

The leading cause of disease burden and death across the globe is still cardiovascular disease (CVD), with low, low-middle, and middle sociodemographic index (SDI) regions carrying the heaviest burden, according to a study.

CVD tops disease burden, death cause worldwide

11 Dec 2025

Transition model eases move from paediatric to adult care for cSLE patients

A recent study has demonstrated the effectiveness of a structured paediatric-adult dyad transition care model in encouraging prompt initial attendance and ensuring continuity of care for patients with childhood-onset systemic lupus erythematosus (cSLE) during the critical transition from paediatric to adult healthcare.

Transition model eases move from paediatric to adult care for cSLE patients

ICONIC-LEAD affirms oral icotrokinra benefits in plaque psoriasis