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Novel MET kinase inhibitor counteracts TKI resistance in NSCLC
Treatment with SCC244, a novel small molecule inhibitor of the enzyme MET kinase, appears to help overcome the resistance to tyrosine kinase inhibitors (TKI) mediated by MET amplification in nonsmall cell lung cancer (NSCLC), reports a new study presented at the recent 2022 European Society for Medical Oncology Asia Congress (ESMO Asia 2022).
Novel MET kinase inhibitor counteracts TKI resistance in NSCLC
09 Dec 2022
Add-on radiation therapy poses higher cardiovascular risk in stage III NSCLC
The addition of radiation therapy to chemotherapy may be more detrimental than beneficial in patients with resectable stage III nonsmall‐cell lung cancer (NSCLC), being associated with a heightened risk of severe cardiac events, as shown in a study.
Add-on radiation therapy poses higher cardiovascular risk in stage III NSCLC
09 Dec 2022
Progestin shows therapeutic potential in PR-positive endometrial cancer
Progestin therapy appears to yield high response rates in advanced stage and recurrent endometrial cancer that is positive for progesterone receptor (PR) expression, while having low toxicity, according to a study.
Progestin shows therapeutic potential in PR-positive endometrial cancer
08 Dec 2022
Erenumab works well in chronic migraine patients across Asia
Erenumab proves to be effective at lowering the number of monthly migraine days in Asian patients with chronic migraine while having a favourable safety profile, according to the results of DRAGON study.
Erenumab works well in chronic migraine patients across Asia
06 Dec 2022
Weekly somapacitan on par with daily growth hormone in children
Weekly somapacitan is noninferior to daily growth hormone (GH) in terms of height velocity (HV), with comparable safety and mean insulin-like growth factor-1 standard deviation score (IGF-1 SDS) levels in treatment-naïve children with growth hormone deficiency (GHD), a study has shown.