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Early initiation of a soluble guanylate cyclase stimulator in an elderly patient with refractory HFrEF
Early initiation of a soluble guanylate cyclase stimulator in an elderly patient with refractory HFrEF
23 Apr 2025 byDr. Cyril Ko, Specialist in Cardiology, Private practice, Hong Kong

The patient was an 80-year-old male with multiple comorbidities, including diabetes mellitus controlled with a sodium-glucose cotransporter-2 inhibitor (SGLT2i), hypertension and coronary artery disease, for which he underwent stenting in October 2023. He also had a pacemaker implanted for heart block. His left ventricular ejection fraction (LVEF) ranged between 40–50 percent. For several years, he had been managed as an outpatient for mild heart failure (HF) symptoms and maintained independence in activities of daily living (ADL).

Early initiation of a soluble guanylate cyclase stimulator in an elderly patient with refractory HFrEF
23 Apr 2025