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$Testosterone offers no long-distance mobility benefit to women with hip fracture$

Testosterone offers no long-distance mobility benefit to women with hip fracture

27 May 2025

Use of topical testosterone therapy in addition to supervised exercise training does little to improve long-distance walking ability for older women recovering from a hip fracture, according to the phase III STEP-HI randomized clinical trial.

Testosterone offers no long-distance mobility benefit to women with hip fracture

27 May 2025

Seladelpar improves cholestatic, liver injury markers in patients with PBC, cirrhosis

27 May 2025 by

Treatment with seladelpar led to improvements in markers of cholestasis and liver injury in patients with primary biliary cholangitis (PBC) and compensated cirrhosis, according to an additional analysis of the RESPONSE trial presented at DDW 2025.

Seladelpar improves cholestatic, liver injury markers in patients with PBC, cirrhosis

27 May 2025

Etrasimod shows promise in eosinophilic oesophagitis

26 May 2025

In the treatment of eosinophilic oesophagitis, the use of etrasimod is well tolerated and results in sustained histological and endoscopic improvements and symptom reduction, according to the results of a phase II study.

Etrasimod shows promise in eosinophilic oesophagitis

26 May 2025

Superior IBD control achieved with biomarker-guided therapy standard care

26 May 2025 by

Biomarker-informed molecular guidance improves anti-TNF therapy outcomes in patients with inflammatory bowel disease (IBD), increasing the likelihood of achieving disease control when compared with standard “best care,” as shown in the GUIDE-IBD trial.

Superior IBD control achieved with biomarker-guided therapy standard care

26 May 2025

Monitor kidney function to reduce CV risk in CKD patients: study

26 May 2025

In patients with stable chronic kidney disease (CKD), the risk of cardiomyopathy caused by kidney disease appears to be greater than the risk of CKD progression due to heart disease, suggests a study, noting that these observational analyses do not establish causality.

Monitor kidney function to reduce CV risk in CKD patients: study

26 May 2025

High, increasing BMI ups risk of adulthood OSA

26 May 2025 by

Individuals with high or continuously increasing BMI from childhood to middle age are at greater risk of developing obstructive sleep apnoea (OSA) later in life, reveals a study.

High, increasing BMI ups risk of adulthood OSA

26 May 2025

Investigational Gal3 inhibitor NAVIGATEs MASH treatment field

26 May 2025 by

The galectin-3 (Gal3) inhibitor belapectin, given at the established 2-mg dose, demonstrates its treatment potential for metabolic dysfunction-associated steatohepatitis (MASH) cirrhosis and portal hypertension (PH) in the phase IIb/III NAVIGATE trial.

Investigational Gal3 inhibitor NAVIGATEs MASH treatment field

26 May 2025

Personalizing upfront treatment options for advanced EGFRm NSCLC

26 May 2025 by

This article will summarize the latest developments in the first-line management of advanced EGFRm NSCLC and highlight key consideration factors.

Personalizing upfront treatment options for advanced EGFRm NSCLC

26 May 2025

Dietary fibre intake protective against stroke, mortality

26 May 2025

Consuming high amounts of dietary fibre helps reduce the risk of stroke and of all-cause mortality among individuals who have already survived a stroke, according to a study.

Dietary fibre intake protective against stroke, mortality

26 May 2025

Novel GLP-1/FGF21 dual agonist shows promise in treatment of MASLD with T2DM

26 May 2025

The glucagon-like peptide-1 (GLP-1) and fibroblast growth factor 21 (FGF21) dual agonist HEC88473 demonstrates an acceptable safety profile and potential efficacy in the management of patients with metabolic dysfunction-associated steatotic liver disease (MASLD) and type 2 diabetes mellitus (T2DM).

Novel GLP-1/FGF21 dual agonist shows promise in treatment of MASLD with T2DM

26 May 2025

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Testosterone offers no long-distance mobility benefit to women with hip fracture

Testosterone offers no long-distance mobility benefit to women with hip fracture

Seladelpar improves cholestatic, liver injury markers in patients with PBC, cirrhosis

Seladelpar improves cholestatic, liver injury markers in patients with PBC, cirrhosis

Etrasimod shows promise in eosinophilic oesophagitis

Etrasimod shows promise in eosinophilic oesophagitis

Superior IBD control achieved with biomarker-guided therapy standard care

Superior IBD control achieved with biomarker-guided therapy standard care

Monitor kidney function to reduce CV risk in CKD patients: study

Monitor kidney function to reduce CV risk in CKD patients: study

High, increasing BMI ups risk of adulthood OSA

High, increasing BMI ups risk of adulthood OSA

Investigational Gal3 inhibitor NAVIGATEs MASH treatment field

Investigational Gal3 inhibitor NAVIGATEs MASH treatment field

Personalizing upfront treatment options for advanced EGFRm NSCLC

Personalizing upfront treatment options for advanced EGFRm NSCLC

Dietary fibre intake protective against stroke, mortality

Dietary fibre intake protective against stroke, mortality

Novel GLP-1/FGF21 dual agonist shows promise in treatment of MASLD with T2DM

Novel GLP-1/FGF21 dual agonist shows promise in treatment of MASLD with T2DM