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Linaclotide improves bowel symptoms in children with functional constipation

16 May 2025 by

Treatment with linaclotide led to significantly improved symptoms of incomplete bowel evacuation and straining in paediatric patients aged 6–17 years with functional constipation, according to a phase III study presented at DDW 2025.

Linaclotide improves bowel symptoms in children with functional constipation

16 May 2025

AI model shows potential in reading paediatric elbow radiographs

14 May 2025 by

A deep learning artificial intelligence (AI) model demonstrates good area under the receiver operating characteristic curve (AUROC) and higher sensitivity in the binomial classification of paediatric elbow radiographs when compared to emergency department (ED) physicians, reports a Singapore study.

AI model shows potential in reading paediatric elbow radiographs

14 May 2025

TAF prophylaxis prevents mother-to-child transmission of HBV

13 May 2025

Treatment with tenofovir alafenamide (TAF) is generally safe and effective for the prevention of hepatitis B virus (HBV) mother-to-child transmission (MTCT), reports a study, noting that the expected 8-week prenatal duration is feasible.

TAF prophylaxis prevents mother-to-child transmission of HBV

13 May 2025

HCQ improves platelet counts in children with chronic ITP

07 May 2025

Treatment with hydroxychloroquine (HCQ) results in higher platelet counts in children with chronic immune thrombocytopenia (ITP), a study has shown. In addition, its efficacy is not associated with the baseline antinuclear antibody (ANA) level.

HCQ improves platelet counts in children with chronic ITP

07 May 2025

Single primaquine dose helps block malaria transmission in children

06 May 2025

A single low primaquine dose appears to safely and efficaciously reduce transmission of Plasmodium falciparum in children, according to the results of a meta-analysis.

Single primaquine dose helps block malaria transmission in children

06 May 2025

Exercise therapy plus family intervention beneficial to children with ADHD

05 May 2025

Children with attention deficit and hyperactivity disorder (ADHD) who undergo exercise therapy combined with family intervention appear to show improvements in attention and executive function, social functioning, and school performance, according to a retrospective cohort study.

Exercise therapy plus family intervention beneficial to children with ADHD

05 May 2025

Breastfeeding reduces risk of infant RTIs

02 May 2025

Infants who have been fully breastfed for 6 months up to at least 1 year appear to have a lower risk of subsequent respiratory tract infections (RTIs) and hospitalization from RTIs, a study has shown.

Breastfeeding reduces risk of infant RTIs

02 May 2025

Original-New-Drug-Application-Approvals-by-US-FDA--1-15-April-2025

02 May 2025

New drug applications approved by US FDA as of 1-15 April 2025 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original-New-Drug-Application-Approvals-by-US-FDA--1-15-April-2025

02 May 2025

Childhood adversity predicts psychosis onset

30 Apr 2025

Children who have been exposed to early adversities are at increased odds of developing psychosis, suggests a study.

Childhood adversity predicts psychosis onset

30 Apr 2025

Single-dose baloxavir reduces household transmission of influenza

30 Apr 2025 by

A single dose of baloxavir given to an index patient (IP) reduces the odds of influenza transmission to untreated household contacts (HHCs) by 32 percent vs placebo, according to the results of the phase IIIb CENTERSTONE trial.

Single-dose baloxavir reduces household transmission of influenza

30 Apr 2025

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Linaclotide improves bowel symptoms in children with functional constipation

Linaclotide improves bowel symptoms in children with functional constipation

AI model shows potential in reading paediatric elbow radiographs

AI model shows potential in reading paediatric elbow radiographs

TAF prophylaxis prevents mother-to-child transmission of HBV

TAF prophylaxis prevents mother-to-child transmission of HBV

HCQ improves platelet counts in children with chronic ITP

HCQ improves platelet counts in children with chronic ITP

Single primaquine dose helps block malaria transmission in children

Single primaquine dose helps block malaria transmission in children

Exercise therapy plus family intervention beneficial to children with ADHD

Exercise therapy plus family intervention beneficial to children with ADHD

Breastfeeding reduces risk of infant RTIs

Breastfeeding reduces risk of infant RTIs

Original-New-Drug-Application-Approvals-by-US-FDA--1-15-April-2025

Original-New-Drug-Application-Approvals-by-US-FDA--1-15-April-2025

Childhood adversity predicts psychosis onset

Childhood adversity predicts psychosis onset

Single-dose baloxavir reduces household transmission of influenza

Single-dose baloxavir reduces household transmission of influenza