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Mirikizumab beneficial in paediatric ulcerative colitis

25 Nov 2025

The humanised immunoglobulin G4 monoclonal antibody mirikizumab appears to be safe and efficacious in the treatment of children with moderately to severely active ulcerative colitis, according to a phase II study.

Mirikizumab beneficial in paediatric ulcerative colitis

25 Nov 2025

Respiratory infections pose major disease burden in hospitalized children

24 Nov 2025 by

Children hospitalized for viral respiratory diseases carry a significant burden of illness, reports a study.

Respiratory infections pose major disease burden in hospitalized children

24 Nov 2025

Mediastinitis rare but fatal after paediatric cardiac surgery

24 Nov 2025

A recent study has found a low incidence of mediastinitis, a rare complication of neonatal cardiac surgery, at a tertiary referral centre, but mortality is high. Fungal infection is the main predictor of death.

Mediastinitis rare but fatal after paediatric cardiac surgery

24 Nov 2025

Dalbavancin safe, effective in paediatric Gram-positive infections

23 Nov 2025

Consolidation treatment with dalbavancin appears safe and effective for the treatment of severe infections caused by Gram-positive microorganisms in children, suggests a study.

Dalbavancin safe, effective in paediatric Gram-positive infections

23 Nov 2025

Oseltamivir can keep children with flu out of the ICU

21 Nov 2025 by

Treatment with oseltamivir in children hospitalized with influenza helps prevent progression into a state requiring ICU admission and shorten the length of hospital stay, as shown in a US-based retrospective study.

Oseltamivir can keep children with flu out of the ICU

21 Nov 2025

Obesity, physical activity influence subsequent neoplasm risk in childhood cancer survivors

21 Nov 2025

Obesity contributes to an increased risk of multiple subsequent neoplasms in childhood cancer survivors, but higher physical activity confers a protective effect, according to a retrospective study.

Obesity, physical activity influence subsequent neoplasm risk in childhood cancer survivors

21 Nov 2025

Acute kidney injury in preemies tied to poor neurodevelopmental outcomes

19 Nov 2025

Preterm infants with acute kidney injury (AKI) may have poor neurodevelopmental outcomes, according to a study.

Acute kidney injury in preemies tied to poor neurodevelopmental outcomes

19 Nov 2025

Large French study clears mRNA-based COVID-19 vaccines of teratogenic risk

15 Nov 2025 by

Receipt of messenger RNA (mRNA)-based COVID-19 vaccine during pregnancy does not appear to be associated with an increased risk of any major congenital malformations, according to new research from France.

Large French study clears mRNA-based COVID-19 vaccines of teratogenic risk

15 Nov 2025

Limited sugar exposure in early life may prevent CVD events in adulthood

15 Nov 2025 by

Restricting sugar exposure in utero and during infancy appears protective against the risks of several cardiovascular outcomes and delays disease onset later in life, suggests a study.

Limited sugar exposure in early life may prevent CVD events in adulthood

15 Nov 2025

Telitacicept beneficial in childhood-onset SLE

14 Nov 2025

In the management of patients with childhood-onset systemic lupus erythematosus (cSLE), combining telitacicept with standard of care (SoC) appears to reduce disease activity, steroid exposure, and immunological marker concentrations, effects comparable to those observed with belimumab, according to a study.

Telitacicept beneficial in childhood-onset SLE

14 Nov 2025

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Mirikizumab beneficial in paediatric ulcerative colitis

Mirikizumab beneficial in paediatric ulcerative colitis

Respiratory infections pose major disease burden in hospitalized children

Respiratory infections pose major disease burden in hospitalized children

Mediastinitis rare but fatal after paediatric cardiac surgery

Mediastinitis rare but fatal after paediatric cardiac surgery

Dalbavancin safe, effective in paediatric Gram-positive infections

Dalbavancin safe, effective in paediatric Gram-positive infections

Oseltamivir can keep children with flu out of the ICU

Oseltamivir can keep children with flu out of the ICU

Obesity, physical activity influence subsequent neoplasm risk in childhood cancer survivors

Obesity, physical activity influence subsequent neoplasm risk in childhood cancer survivors

Acute kidney injury in preemies tied to poor neurodevelopmental outcomes

Acute kidney injury in preemies tied to poor neurodevelopmental outcomes

Large French study clears mRNA-based COVID-19 vaccines of teratogenic risk

Large French study clears mRNA-based COVID-19 vaccines of teratogenic risk

Limited sugar exposure in early life may prevent CVD events in adulthood

Limited sugar exposure in early life may prevent CVD events in adulthood

Telitacicept beneficial in childhood-onset SLE

Telitacicept beneficial in childhood-onset SLE