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Sustained PFS benefit in breast cancer with palbociclib + exemestane with ovarian function suppression

09 Mar 2025

Treatment with palbociclib plus exemestane with ovarian function suppression does not appear to produce improvements in overall survival (OS), although it yields sustained increases in progression-free survival (PFS) as compared with capecitabine in premenopausal patients with hormone receptor-positive, HER2-negative metastatic breast cancer, according to updated data from the phase II Young-PEARL study.

Sustained PFS benefit in breast cancer with palbociclib + exemestane with ovarian function suppression

09 Mar 2025

Foetal malformation risk high in ART-conceived pregnancies of women with epilepsy

06 Mar 2025

Conception via assisted reproductive technology (ART) carries an increased risk of foetal malformation among women with epilepsy, according to a study.

Foetal malformation risk high in ART-conceived pregnancies of women with epilepsy

06 Mar 2025

Eating behaviour, food choices play role in pelvic floor disorders

06 Mar 2025 by

Disordered eating, along with consumption of certain food items, may predispose middle-aged women to pelvic floor disorders, as suggested in a study.

Eating behaviour, food choices play role in pelvic floor disorders

06 Mar 2025

Eating disorders tied to nighttime eating, menopausal symptom severity

05 Mar 2025

Climacteric women with eating disorders are more likely to exhibit night eating habits and experience more severe symptoms of menopause, as reported in a descriptive study.

Eating disorders tied to nighttime eating, menopausal symptom severity

05 Mar 2025

Nonmalignant gynaecological diseases linked to cardiovascular, cerebrovascular disease

02 Mar 2025

Individuals with nonmalignant gynaecological diseases appear to be at increased risk of cardiovascular and cerebrovascular diseases, according to the results of a systematic review and meta-analysis.

Nonmalignant gynaecological diseases linked to cardiovascular, cerebrovascular disease

02 Mar 2025

APOSTEL 8: Tocolytic benefit for threatened preterm birth called into question

01 Mar 2025 by

In the management of threatened preterm birth between 30 and 34 weeks of gestation, atosiban falls short of improving neonatal outcomes when compared with placebo, according to the results of the APOSTEL 8 trial.

APOSTEL 8: Tocolytic benefit for threatened preterm birth called into question

01 Mar 2025

Severe maternal morbidity up by fourfold in presence of CRC

27 Feb 2025 by

Pregnant women with colorectal cancer (CRC) face a considerably increased likelihood of severe maternal morbidity, including disseminated intravascular coagulation, acute respiratory distress syndrome, and hysterectomy, among others, according to a study.

Severe maternal morbidity up by fourfold in presence of CRC

27 Feb 2025

Aspirin for preeclampsia prophylaxis: Does dose matter?

27 Feb 2025 by

Doubling up on the daily aspirin dose of 81 mg appears to yield no significant protective effect against the incidence of preeclampsia in high-risk pregnancies, suggests findings from the ASAPP* study presented at SMFM 2025.

Aspirin for preeclampsia prophylaxis: Does dose matter?

27 Feb 2025

Antenatal corticosteroid reduces neonatal morbidities in late preterm twins

25 Feb 2025 by

Antenatal corticosteroid betamethasone administration significantly reduces the risk of neonatal respiratory morbidity in women with twin pregnancies at risk of late preterm delivery, according to the ACTWIN* trial presented at SMFM 2025.

Antenatal corticosteroid reduces neonatal morbidities in late preterm twins

25 Feb 2025

Hypertensive disorders of pregnancy linked to subsequent atrial fibrillation

22 Feb 2025

Women who had hypertensive disorders of pregnancy (HDP) during their first delivery face an increased risk of incident atrial fibrillation (AF), particularly those who had more severe de novo HDP diagnoses as well as chronic hypertension in pregnancy, according to a retrospective study.

Hypertensive disorders of pregnancy linked to subsequent atrial fibrillation

22 Feb 2025

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Sustained PFS benefit in breast cancer with palbociclib + exemestane with ovarian function suppression

Sustained PFS benefit in breast cancer with palbociclib + exemestane with ovarian function suppression

Foetal malformation risk high in ART-conceived pregnancies of women with epilepsy

Foetal malformation risk high in ART-conceived pregnancies of women with epilepsy

Eating behaviour, food choices play role in pelvic floor disorders

Eating behaviour, food choices play role in pelvic floor disorders

Eating disorders tied to nighttime eating, menopausal symptom severity

Eating disorders tied to nighttime eating, menopausal symptom severity

Nonmalignant gynaecological diseases linked to cardiovascular, cerebrovascular disease

Nonmalignant gynaecological diseases linked to cardiovascular, cerebrovascular disease

APOSTEL 8: Tocolytic benefit for threatened preterm birth called into question

APOSTEL 8: Tocolytic benefit for threatened preterm birth called into question

Severe maternal morbidity up by fourfold in presence of CRC

Severe maternal morbidity up by fourfold in presence of CRC

Aspirin for preeclampsia prophylaxis: Does dose matter?

Aspirin for preeclampsia prophylaxis: Does dose matter?

Antenatal corticosteroid reduces neonatal morbidities in late preterm twins

Antenatal corticosteroid reduces neonatal morbidities in late preterm twins

Hypertensive disorders of pregnancy linked to subsequent atrial fibrillation

Hypertensive disorders of pregnancy linked to subsequent atrial fibrillation