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SAFE score-based approach more effective than current guidelines for liver fibrosis

02 Nov 2025

A recent study has found the proposed population risk stratification approach using the Steatosis-Associated Fibrosis Estimator (SAFE) score to be simpler and more effective than current guidelines.

SAFE score-based approach more effective than current guidelines for liver fibrosis

02 Nov 2025

Sultiame shows therapeutic potential in obstructive sleep apnoea

02 Nov 2025

In patients with obstructive sleep apnoea (OSA), treatment with sultiame yields improvements in nocturnal hypoxia, sleep quality, and excessive daytime sleepiness, according to a phase II trial.

Sultiame shows therapeutic potential in obstructive sleep apnoea

02 Nov 2025

AIH linked to higher lymphoma, myeloma risks, but not to extrahepatic malignancy

01 Nov 2025

Patients with autoimmune hepatitis (AIH) do not show an increased risk of overall extrahepatic malignancy compared with controls, but they appear to be at greater risk of lymphoma or myeloma, independent of immunosuppressant use, suggests a study.

AIH linked to higher lymphoma, myeloma risks, but not to extrahepatic malignancy

01 Nov 2025

Denifanstat reduces lesions in acne vulgaris

01 Nov 2025 by

The fatty acid synthase inhibitor denifanstat shows potential for treating moderate-to-severe acne vulgaris, with good safety and tolerability, as demonstrated in a study from China presented at EADV 2025.

Denifanstat reduces lesions in acne vulgaris

01 Nov 2025

Mild endoscopic disease activity poses risk for older adults with IBD

31 Oct 2025

For older adults with inflammatory bowel disease (IBD), mild endoscopic activity is linked to adverse IBD-specific and morbidity-related outcomes relative to endoscopic remission, as reported in a retrospective study.

Mild endoscopic disease activity poses risk for older adults with IBD

31 Oct 2025

Exercise neutralizes dyslipidaemia risk by modulating gut health

31 Oct 2025 by

New research suggests that engaging in moderate-to-vigorous physical activity can counteract the harmful association between sedentary behaviour and dyslipidaemia by promoting a healthier, more diverse community of gut bacteria.

Exercise neutralizes dyslipidaemia risk by modulating gut health

31 Oct 2025

Setmelanotide delivers long-term benefits in adults with obesity

31 Oct 2025

The melanocortin-4 receptor agonist setmelanotide has demonstrated long-term clinical benefit and an acceptable safety profile in adults with monogenic or syndromic obesity, reports a study.

Setmelanotide delivers long-term benefits in adults with obesity

31 Oct 2025

CTC-DMARD lowers risk of treatment failure in nonanterior sarcoidosis uveitis

31 Oct 2025 by

Treatment with corticosteroid (CTC) plus conventional disease-modifying antirheumatic drug (C-DMARD) demonstrates an acceptable safety profile and appears to be more efficient than CTC alone in patients with nonanterior sarcoidosis-related uveitis, reports a study.

CTC-DMARD lowers risk of treatment failure in nonanterior sarcoidosis uveitis

31 Oct 2025

HPV infection may elevate glaucoma risk

31 Oct 2025

Infection with the human papillomavirus (HPV) appears to increase the risk of developing glaucoma, a recent study has shown.

HPV infection may elevate glaucoma risk

31 Oct 2025

Ketamine infusions no better than midazolam infusions for inpatient depression treatment

31 Oct 2025 by

Administering serial ketamine infusions does not show a clear advantage over serial midazolam infusions for reducing depressive symptoms in patients receiving standard inpatient psychiatric care, according to the KARMA-Dep 2 trial.

Ketamine infusions no better than midazolam infusions for inpatient depression treatment

31 Oct 2025

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SAFE score-based approach more effective than current guidelines for liver fibrosis

SAFE score-based approach more effective than current guidelines for liver fibrosis

Sultiame shows therapeutic potential in obstructive sleep apnoea

Sultiame shows therapeutic potential in obstructive sleep apnoea

AIH linked to higher lymphoma, myeloma risks, but not to extrahepatic malignancy

AIH linked to higher lymphoma, myeloma risks, but not to extrahepatic malignancy

Denifanstat reduces lesions in acne vulgaris

Denifanstat reduces lesions in acne vulgaris

Mild endoscopic disease activity poses risk for older adults with IBD

Mild endoscopic disease activity poses risk for older adults with IBD

Exercise neutralizes dyslipidaemia risk by modulating gut health

Exercise neutralizes dyslipidaemia risk by modulating gut health

Setmelanotide delivers long-term benefits in adults with obesity

Setmelanotide delivers long-term benefits in adults with obesity

CTC-DMARD lowers risk of treatment failure in nonanterior sarcoidosis uveitis

CTC-DMARD lowers risk of treatment failure in nonanterior sarcoidosis uveitis

HPV infection may elevate glaucoma risk

HPV infection may elevate glaucoma risk

Ketamine infusions no better than midazolam infusions for inpatient depression treatment

Ketamine infusions no better than midazolam infusions for inpatient depression treatment