News &amp; Updates

New drug applications approved by US FDA as of 16-30 September 2025 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (16-30 September 2025)

Original-New-Drug-Application-Approvals-by-US-FDA--1-15-September-2025

New drug applications approved by US FDA as of 1-15 September 2025 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original-New-Drug-Application-Approvals-by-US-FDA--1-15-September-2025

Functional outcome in hip OA better with cycling plus education vs physiotherapy care

For individuals with hip osteoarthritis (OA), a group-based cycling and education programme (CHAIN) yields greater improvements in function compared with usual physiotherapy care, as shown in a study from the UK.

Functional outcome in hip OA better with cycling plus education vs physiotherapy care

Adverse pregnancy outcomes put women at risk of AF

Women with a history of preterm delivery, hypertensive disorders of pregnancy, and several other pregnancy complications face an increased long-term risk of atrial fibrillation (AF), as suggested in a study.

Adverse pregnancy outcomes put women at risk of AF

Will ChatGPT pass a neurosurgery board examination?

Neurosurgery residents appear to remain superior to ChatGPT in answering neurosurgery board examination-like questions, suggests a study in the Philippines. However, the studies included in the meta-analysis have high heterogeneity.

Will ChatGPT pass a neurosurgery board examination?

Sexual distress in women tied to pain, satisfaction

Distress about low sexual function correlates positively with the severity of sexual pain and negatively with sexual satisfaction among women, reports a study.

Sexual distress in women tied to pain, satisfaction

Childhood abuse linked to sexual compulsivity, violent sexual behaviour

Impulsivity appears to be associated with violent sexual behaviour (VSB) in individuals with compulsive sexual behaviour (CSB) who suffered childhood abuse, reveals a study.

Childhood abuse linked to sexual compulsivity, violent sexual behaviour

Free school meals tied to improved child health

A US cohort study of schools matched to child and adolescent patient medical records from a network of community health organizations found an association between school participation in the Community Eligibility Provision (CEP) programme and a net reduction in blood pressure (BP) outcomes.

Free school meals tied to improved child health

30 Oct 2025

Temperature extremes detrimental to heart failure patients

Short-term exposure to either low or high temperatures carries an increased risk of mortality in patients with heart failure (HF), as suggested in a study.

Temperature extremes detrimental to heart failure patients

Cagrilintide-semaglutide tied to weight loss in adults with obesity, T2D

Combination treatment with cagrilintide and semaglutide significantly reduced body weight in patients with overweight or obesity and type 2 diabetes (T2D), according to the REDEFINE 2 trial presented at EASD 2025.

Cagrilintide-semaglutide tied to weight loss in adults with obesity, T2D