News &amp; Updates

In the treatment of infertility in women with ovarian or deep infiltrating endometriosis, in-vitro fertilization (IVF) is associated with better chances of achieving a live birth compared with endometriosis surgery, according to a pragmatic, partially randomized patient preference trial.

Sacituzumab govitecan plus pembrolizumab falls short of prolonging PFS in metastatic breast cancer

Combination treatment with sacituzumab govitecan (SG) and pembrolizumab does not improve outcomes in hormone receptor (HR)-positive/human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer (MBC) unselected by programmed death-ligand 1 (PD-L1), as shown in a phase II trial.

Walnut-based low-carbohydrate diet helps reduce fat in people with central obesity

Adherence to a walnut-based low-carbohydrate diet (w-LCD) results in substantially faster and greater fat reduction over time among individuals with central obesity compared with a high-carbohydrate, low-fat diet (HCD), according to a study.

04 Nov 2026

No need for low-dose aspirin during ESD in patients with low thrombotic risk: study

A recent study has found no evidence of the noninferiority of low-dose aspirin (LDA) continuation over discontinuation during gastric endoscopic submucosal dissection (ESD) in patients with gastric mucosal neoplasms and low thrombotic risk.

Multiple vascular risk factors raise risk of late-onset epilepsy

Modifiable vascular risk factors and a history of stroke are associated with an increased risk of late-onset epilepsy, according to a meta-analysis.

Trispecific antibody meets EASI-75 target in AD

In a two-stage phase II dose-ranging trial, once-monthly treatment with tilrekimig yields high clinical response rates and reduces itching in biologic-naïve adults with mild-to-moderate atopic dermatitis (AD).

04 Nov 2026

Asthma: No difference in pneumonia risk between budesonide and fluticasone users

A territory-wide retrospective study of >16,000 adult patients with moderate-to-severe asthma finds no difference in risk of pneumonia between budesonide and fluticasone propionate (FP) or fluticasone furoate (FF) users.

04 Nov 2026

Single intranasal mebufotenin dose yields rapid effect in treatment-resistant depression

03 Nov 2026 by

A single intranasal dose of the psychedelic mebufotenin benzoate helps improve symptoms in adults with treatment-resistant depression, with the benefit emerging as early as day 1 after dosing and persisting for 8 weeks, according to a phase IIb trial said to be the largest clinical evaluation to date of mebufotenin administered as a nose spray.

Antibiotic use for GI infection ups risk of developing IBS

Treatment with antibiotics appears to increase the risk of irritable bowel syndrome (IBS) development, particularly following a gastrointestinal (GI) infection, suggests a study.

$Risankizumab improves outcomes in refractory patients with CD$

Risankizumab improves outcomes in refractory patients with CD

03 Nov 2026 by

Treatment with risankizumab results in fast and sustained favourable clinical, endoscopic, and radiologic outcomes in patients with Crohn’s disease (CD), a real-world study has shown.