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5-year data back omission of sentinel lymph node biopsy in early-stage breast cancer

19 Jan 2026 by

Sentinel lymph node biopsy (SLNB) may be safely omitted after breast-conserving therapy in patients with early-stage, node-negative breast cancer, with 5-year data from the BOOG 13-08 trial showing no difference in regional recurrence-free and distant disease-free survival outcomes whether or not SLNB was performed.

5-year data back omission of sentinel lymph node biopsy in early-stage breast cancer

19 Jan 2026

Breastfeeding may be protective against depression, anxiety in mums

19 Jan 2026

Women who have ever breastfed appear to have reduced long-term risk of depression and anxiety, as suggested in a study.

Breastfeeding may be protective against depression, anxiety in mums

19 Jan 2026

No rise in breast cancer risk for young BRCA carriers on menopausal hormone therapy

18 Jan 2026 by

For young women with a pathogenic variant in BRCA1 or BRCA2, initiating hormone replacement therapy following surgical menopause does not appear to significantly increase the risk of breast cancer, with oestrogen-alone therapy even conferring protection, according to a study.

No rise in breast cancer risk for young BRCA carriers on menopausal hormone therapy

18 Jan 2026

Oral anticoagulant therapy tied to risk of abnormal uterine bleeding

16 Jan 2026

Oral anticoagulant users, particularly young women, have an increased likelihood of abnormal uterine bleeding, according to a nested matched case–control study.

Oral anticoagulant therapy tied to risk of abnormal uterine bleeding

16 Jan 2026

No link between prenatal exposure to acid suppressants and neuropsychiatric disorders in offspring

15 Jan 2026

Exposure to acid-suppressive medications during pregnancy does not appear to contribute to the risk of neuropsychiatric disorders in children, according to a retrospective study.

No link between prenatal exposure to acid suppressants and neuropsychiatric disorders in offspring

15 Jan 2026

EPIK-B5 supports alpelisib plus fulvestrant for HR+, HER2– ABC

15 Jan 2026 by

In the phase III EPIK-B5 study, adding alpelisib, an α-specific PI3K inhibitor, to fulvestrant improves progression-free survival (PFS) in men and postmenopausal women with HR+, HER2− advanced breast cancer (ABC) harbouring a PIK3CA mutation who have progressed on or after treatment with an aromatase inhibitor (AI) and a CDK4/6 inhibitor (CDK4/6i).

EPIK-B5 supports alpelisib plus fulvestrant for HR+, HER2– ABC

15 Jan 2026

Children conceived via ART at increased risk of atopic disease

14 Jan 2026 by

New research shows that children born via assisted reproductive technology (ART) are prone to developing asthma, allergic rhinitis, or atopic dermatitis.

Children conceived via ART at increased risk of atopic disease

14 Jan 2026

Z-drug exposure during early pregnancy not a risk factor for congenital malformations

14 Jan 2026

The use of nonbenzodiazepine sedative hypnotics (Z-drugs) for sleep dysregulation during the first trimester of pregnancy does not appear to contribute to a meaningful increase in the risk of congenital malformations overall, as shown in a study.

Z-drug exposure during early pregnancy not a risk factor for congenital malformations

14 Jan 2026

Fertility factors linked to osteoporosis risk

13 Jan 2026

Women with a history of infertility, miscarriage or stillbirth, and low parity are at increased risk of osteoporosis, as suggested in a study.

Fertility factors linked to osteoporosis risk

13 Jan 2026

Tamoxifen interruption for pregnancy feasible in young breast cancer survivors

08 Jan 2026 by

A real-world Asian study presented at ESMO Asia 2025 supports temporary tamoxifen interruption for young breast cancer survivors who are considering pregnancy.

Tamoxifen interruption for pregnancy feasible in young breast cancer survivors

08 Jan 2026

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5-year data back omission of sentinel lymph node biopsy in early-stage breast cancer

5-year data back omission of sentinel lymph node biopsy in early-stage breast cancer

Breastfeeding may be protective against depression, anxiety in mums

Breastfeeding may be protective against depression, anxiety in mums

No rise in breast cancer risk for young BRCA carriers on menopausal hormone therapy

No rise in breast cancer risk for young BRCA carriers on menopausal hormone therapy

Oral anticoagulant therapy tied to risk of abnormal uterine bleeding

Oral anticoagulant therapy tied to risk of abnormal uterine bleeding

No link between prenatal exposure to acid suppressants and neuropsychiatric disorders in offspring

No link between prenatal exposure to acid suppressants and neuropsychiatric disorders in offspring

EPIK-B5 supports alpelisib plus fulvestrant for HR+, HER2– ABC

EPIK-B5 supports alpelisib plus fulvestrant for HR+, HER2– ABC

Children conceived via ART at increased risk of atopic disease

Children conceived via ART at increased risk of atopic disease

Z-drug exposure during early pregnancy not a risk factor for congenital malformations

Z-drug exposure during early pregnancy not a risk factor for congenital malformations

Fertility factors linked to osteoporosis risk

Fertility factors linked to osteoporosis risk

Tamoxifen interruption for pregnancy feasible in young breast cancer survivors

Tamoxifen interruption for pregnancy feasible in young breast cancer survivors