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5-year PROFILE data: Top-down therapy able to modify longer-term course of CD

17 May 2026 by

A top-down approach of initiating treatment with infliximab plus immunomodulator upon diagnosis of Crohn’s disease (CD) reduces the risk of related abdominal surgery, as well as those of disease progression and hospitalization, as compared with the conventional step-up approach, according to long-term data from the PROFILE trial.

5-year PROFILE data: Top-down therapy able to modify longer-term course of CD

17 May 2026

GLP-1 RA prevents relapse, cuts weight in AUD patients with MetD

16 May 2026 by

Exposure to glucagon-like peptide-1 receptor agonists (GLP-1 RAs) demonstrates superiority over current FDA-approved pharmacotherapies for alcohol use disorder (AUD), reducing the risk of AUD after 1 year of therapy, reports a study presented at DDW 2026.

GLP-1 RA prevents relapse, cuts weight in AUD patients with MetD

16 May 2026

Saturated fat intake ups risk of several cancers

15 May 2026

Individuals with high intakes of total and saturated fats are at increased risks of several cancers, according to a study. On the other hand, polyunsaturated fat intake appears protective.

Saturated fat intake ups risk of several cancers

15 May 2026

Whole-food diet helps ease Crohn’s disease severity

15 May 2026 by

Patients with mild-to-moderate Crohn’s disease (CD) who received the Crohn’s Disease Therapeutic Dietary Intervention (CD-TDI) demonstrate clinical, inflammatory, and barrier improvements, as well as more than threefold greater response than those who received conventional management, reports a study presented at DDW 2026.

Whole-food diet helps ease Crohn’s disease severity

15 May 2026

Gastrin improves pernicious anaemia diagnosis in absence of intrinsic factor antibodies

15 May 2026

Serum gastrin levels enhance the noninvasive diagnosis of pernicious anaemia and lessen the need for endoscopy in B12-deficient patients with isolated anti-parietal cell antibodies (APCA), reports a study.

Gastrin improves pernicious anaemia diagnosis in absence of intrinsic factor antibodies

15 May 2026

Linaclotide improves bowel movements, abdominal symptoms in adults with severe CIC

15 May 2026 by

Treatment with either dose of linaclotide (72 or 145 µg) showed improves bowel movement frequency and abdominal symptoms in adults with severe chronic idiopathic constipation (CIC), according to a post hoc pooled analysis of phase III studies presented at DDW 2026.

Linaclotide improves bowel movements, abdominal symptoms in adults with severe CIC

15 May 2026

Fruit-based, multicomponent foods good for people with functional constipation

14 May 2026

Individuals with functional constipation (FC) may benefit from eating multicomponent and fruit-based foods, suggests a recent study.

Fruit-based, multicomponent foods good for people with functional constipation

14 May 2026

Does coeliac disease increase cardiovascular risk?

13 May 2026

Coeliac disease does not appear to elevate the risk of cardiovascular events, reveals a study, adding that previous associations may have reflected residual confounding rather than a direct pathogenic link.