News &amp; Updates

Obesity shows a significant relationship with several indices of asymptomatic cardiac remodelling and vascular atherosclerosis, according to a study. Moreover, this association is mediated by systolic blood pressure (BP).

Obesity tied to target organ damage indices

Weekly fixed-dosed efsitora as good as daily glargine in T2D

For adult patients with type 2 diabetes (T2D) who are naïve to insulin, a once-weekly fixed-dose efsitora regimen is noninferior to once-daily glargine at reducing blood glucose levels, according to the phase III treat-to-target QWINT-1 trial.

Weekly fixed-dosed efsitora as good as daily glargine in T2D

Nirmatrelvir–ritonavir combo not better than ritonavir alone in adults with long COVID

For individuals with long COVID, treatment with nirmatrelvir plus ritonavir does not appear to yield improvements in health outcomes when compared with ritonavir alone, according to a phase II study.

Nirmatrelvir–ritonavir combo not better than ritonavir alone in adults with long COVID

No excess liver cancer risk seen with oral contraceptive use

03 Aug 2025 by

Two large prospective cohorts show no evidence of an association between the use of oral contraceptives and the risk of liver cancer.

No excess liver cancer risk seen with oral contraceptive use

COVID-19 survivors prone to hypertension, CVD

03 Aug 2025 by

Survivors of COVID-19 remain at risk of long-term cardiovascular events, including elevated blood pressure (BP) and endothelial dysfunction, reveals a study.

COVID-19 survivors prone to hypertension, CVD

03 Aug 2025

Higher superior to low atropine dose, orthokeratology for paediatric myopia

Treatment with 0.04% atropine appears to improve myopia control in children and teens compared with 0.01% atropine or orthokeratology, despite a higher incidence of photophobia, according to a study.

Higher superior to low atropine dose, orthokeratology for paediatric myopia

TENS no better than sham for managing pain during early procedural abortion

In the management of pain during first-trimester procedural abortion, transcutaneous electrical nerve stimulation (TENS) does not prove superior to sham stimulation, as shown in a study.

TENS no better than sham for managing pain during early procedural abortion

Genetic overlap influences comorbidity of PAU, psychiatric disorders

Some shared genetic factors can affect the comorbidity of problematic alcohol use (PAU) and psychiatric disorders, according to a study. Specifically, TTC12 and ANKK1 show a potentially causal association with comorbid conditions.

Genetic overlap influences comorbidity of PAU, psychiatric disorders

Risk of MACE higher with sulfonylureas vs DPP4is

In the treatment of patients with type 2 diabetes, sulfonylureas pose an increased risk of major adverse cardiovascular events (MACE) compared with dipeptidyl peptidase 4 inhibitors (DPP4is), according to a study.

Risk of MACE higher with sulfonylureas vs DPP4is

Bimekizumab shows long-term benefits across axSpA spectrum

02 Aug 2025 by

Treatment with bimekizumab showed sustained efficacy for up to 3 years in patients with nonradiographic (nr) and radiographic (r) axial spondyloarthritis (axSpA), based on a pooled analysis of the two phase III studies (BE MOBILE 1 and 2) and combined open-label extension (OLE) study presented at EULAR 2025.

Bimekizumab shows long-term benefits across axSpA spectrum