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Common blood test predicts which AD patients will have rapid cognitive decline

11 Sep 2025 by

Insulin resistance, detected through the routine triglyceride-glucose (TyG) index, identifies individuals with early Alzheimer’s disease (AD) who are four times more likely to experience rapid cognitive decline, findings from a new study presented at EAN 2025 suggest.

Common blood test predicts which AD patients will have rapid cognitive decline

11 Sep 2025

Sotrovimab for COVID-19 pneumonia lowers risk of death in specific subgroup

10 Sep 2025 by

In the treatment of hospitalized patients with COVID-19 pneumonia, the use of the neutralizing monoclonal antibody sotrovimab in addition to usual care reduces mortality but only in the subgroup of those with a high baseline serum SARS-CoV-2 antigen concentration, according to the open-label RECOVERY trial.

Sotrovimab for COVID-19 pneumonia lowers risk of death in specific subgroup

10 Sep 2025

FIGO stage >I predicts vulvar cancer recurrence

10 Sep 2025

In patients with vulvar cancer, International Federation of Gynecology and Obstetrics (FIGO) stage >I is associated with regional and distant recurrences, suggests a study. Factors influencing local recurrence have not been identified.

FIGO stage >I predicts vulvar cancer recurrence

10 Sep 2025

Mirikizumab enhances life quality, productivity of CD patients

10 Sep 2025 by

The use of mirikizumab has improved work productivity and health-related quality of life (HRQoL) in patients with moderately to severely active Crohn’s disease (CD) by week 12, a study has shown. These improvements have been maintained for a year.

Mirikizumab enhances life quality, productivity of CD patients

10 Sep 2025

Regular physical activity helps prevent constipation

10 Sep 2025

People who regularly engage in leisure-time physical activity (PA), 20‒30 min per session for at least 5 days a week, are less likely to develop constipation, suggests a recent study.

Regular physical activity helps prevent constipation

10 Sep 2025

Pancreatic cancer a new Tx target for TTFields?

10 Sep 2025 by

Pain and quality of life (QoL) outcomes from the phase III PANOVA-3 trial reinforce the role of tumour treating fields (TTFields) therapy when added to a chemotherapeutic regimen consisting of gemcitabine/nab-paclitaxel (GnP) for the treatment of individuals with locally advanced pancreatic adenocarcinoma.

Pancreatic cancer a new Tx target for TTFields?

10 Sep 2025

Drinking artificially sweetened beverages during pregnancy a risk factor for GDM

10 Sep 2025

Pregnant women who frequently drink artificially sweetened beverages are at increased risk of gestational diabetes mellitus (GDM), according to a study.

Drinking artificially sweetened beverages during pregnancy a risk factor for GDM

10 Sep 2025

First-line NIVO plus IPI shows ORR, OS benefit in patients with HCC

10 Sep 2025 by

Among Chinese patients with unresectable/advanced hepatocellular carcinoma (HCC), treatment with nivolumab plus ipilimumab (NIVO + IPI) showed better objective response rate (ORR) and overall survival (OS) compared with lenvatinib or sorafenib (LEN/SOR) in the first-line setting, according to the CheckMate 9DW expanded analysis presented at ESMO GI 2025.

First-line NIVO plus IPI shows ORR, OS benefit in patients with HCC

10 Sep 2025

Neuropsychiatric AEs resolve after switch to doravirine-based ARV regimens

10 Sep 2025 by

Switching to a doravirine-based ARV regimen resolves neuropsychiatric AEs that were ongoing during a prior efavirenz-based regimen in DRIVE-AHEAD, with few events persisting 96 weeks after switching — a finding also seen in DRIVE-FORWARD, as shown in post hoc analyses of the OLEs of the two phase III trials

Neuropsychiatric AEs resolve after switch to doravirine-based ARV regimens

10 Sep 2025

Meta-analysis favours clopidogrel over aspirin for secondary prevention in CAD

09 Sep 2025 by

In patients with established coronary artery disease (CAD), clopidogrel appears to provide superior protection against major adverse cardiovascular or cerebrovascular events (MACCE) without increasing the risk of bleeding when compared with aspirin, according to a meta-analysis.

Meta-analysis favours clopidogrel over aspirin for secondary prevention in CAD

09 Sep 2025

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Common blood test predicts which AD patients will have rapid cognitive decline

Common blood test predicts which AD patients will have rapid cognitive decline

Sotrovimab for COVID-19 pneumonia lowers risk of death in specific subgroup

Sotrovimab for COVID-19 pneumonia lowers risk of death in specific subgroup

FIGO stage >I predicts vulvar cancer recurrence

FIGO stage >I predicts vulvar cancer recurrence

Mirikizumab enhances life quality, productivity of CD patients

Mirikizumab enhances life quality, productivity of CD patients

Regular physical activity helps prevent constipation

Regular physical activity helps prevent constipation

Pancreatic cancer a new Tx target for TTFields?

Pancreatic cancer a new Tx target for TTFields?

Drinking artificially sweetened beverages during pregnancy a risk factor for GDM

Drinking artificially sweetened beverages during pregnancy a risk factor for GDM

First-line NIVO plus IPI shows ORR, OS benefit in patients with HCC

First-line NIVO plus IPI shows ORR, OS benefit in patients with HCC

Neuropsychiatric AEs resolve after switch to doravirine-based ARV regimens

Neuropsychiatric AEs resolve after switch to doravirine-based ARV regimens

Meta-analysis favours clopidogrel over aspirin for secondary prevention in CAD

Meta-analysis favours clopidogrel over aspirin for secondary prevention in CAD