News &amp; Updates

Polypharmacy appears common and tends to increase with age in patients with inflammatory bowel disease (IBD), reveals a study.

Polypharmacy prevalent in older adults with IBD

02 Dec 2025

Pharmacist care may reduce hospitalizations in HF patients

Pharmacist interventions in heart failure (HF) across in- and outpatient settings can help lower all-cause and HF hospitalizations, according to a study.

Pharmacist care may reduce hospitalizations in HF patients

Tenapanor relieves constipation in ESKD patients with hyperphosphataemia

Individuals with end-stage kidney disease (ESKD) who have mild-to-severe constipation obtain relief from tenapanor in the post hoc analysis of the phase III BLOCK study.

Tenapanor relieves constipation in ESKD patients with hyperphosphataemia

Higher physical activity in midlife and late life reduces dementia risk

Higher levels of physical activity in midlife and late life, but not in early adulthood, are associated with lower risk of all-cause and Alzheimer’s disease (AD) dementia, a cohort study has shown.

Higher physical activity in midlife and late life reduces dementia risk

Sleep-related disorders up hypertension risk in postmenopausal women

Postmenopausal women with sleep-related disorders face increased risk of hypertension, according to a US-based study.

Sleep-related disorders up hypertension risk in postmenopausal women

Original New Drug Application Approvals by US FDA (16-31 October 2025)

New drug applications approved by US FDA as of 16-31 October 2025 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (16-31 October 2025)

New paradigm in obesity diagnosis & Tx: Look beyond BMI, treat to target to reduce complications

Obesity diagnosis should be based beyond BMI alone and include assessment of excess adiposity, organ dysfunction, daily activity limitations, and obesity-related diseases. A treat-to-target approach should be adopted to achieve disease-modifying effects and reduce obesity-related complications, according to Dr Samantha Hocking of the University of Sydney, Australia, who spoke at the 8^th Endocrinology, Diabetes & Metabolism Hong Kong Annual Meeting (EDM HK 2025).

New paradigm in obesity diagnosis & Tx: Look beyond BMI, treat to target to reduce complications

02 Dec 2025

Perioperative antifungal use helps lower infection risk in penile prosthesis surgery

Perioperative antifungal prophylaxis appears to reduce the risk of infection in patients undergoing inflatable penile prosthesis surgery, suggests a study.

Perioperative antifungal use helps lower infection risk in penile prosthesis surgery

Penile reoperation not uncommon after hypospadias repair in childhood

01 Dec 2025 by

Nearly half of the children who require hypospadias repair need further corrective procedures, normally before the age of five, with low rates of penile reoperations in the second and third decades of life, reports a recent study.

Penile reoperation not uncommon after hypospadias repair in childhood

Current NT-proBNP thresholds underestimates HF outcome in people with high BMI

Current thresholds of N-terminal pro–B-type natriuretic peptide (NT-proBNP) tend to underestimate the risk of adverse heart failure (HF) outcomes among individuals with higher BMI, reveals a study.

Current NT-proBNP thresholds underestimates HF outcome in people with high BMI