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Next-gen sequencing paves way to discovery of novel forms of monogenic diabetes

07 Feb 2022 by

Targeted next-generation sequencing (NGS) appears to be useful for pinpointing causal variants in patients with suspected monogenic diabetes (MD), broadening the spectrum of new pathogenic variants and updating knowledge of the clinical features of patients with various forms of MD, according to a recent study.

Next-gen sequencing paves way to discovery of novel forms of monogenic diabetes

07 Feb 2022

Adherence to lenalidomide deficient in multiple myeloma patients

07 Feb 2022

Adherence to lenalidomide is remarkably lacking among patients with multiple myeloma at 1 year following treatment initiation, a study has found.

Adherence to lenalidomide deficient in multiple myeloma patients

07 Feb 2022

Pandemic interventions help lessen invasive bacterial infections in children

07 Feb 2022 by

The implementation of nonpharmaceutical interventions (NPIs) during the COVID-19 pandemic has significantly reduced the incidences of S. pneumoniae and Salmonella spp. among nine major pathogens of invasive bacterial infection (IBI) in children, reports a study.

Pandemic interventions help lessen invasive bacterial infections in children

07 Feb 2022

Social unrest and pandemic take a toll on HK women’s mental health

07 Feb 2022 by

Exposure to social unrest and the coronavirus disease 2019 (COVID-19) pandemic may increase depressive and post-traumatic stress disorder (PTSD) symptoms among women in Hong Kong, according to a study by the Queen Mary Hospital and University of Hong Kong (HKU).

Social unrest and pandemic take a toll on HK women’s mental health

07 Feb 2022

Adjunctive ketamine safe, effective in alcohol use disorder

07 Feb 2022

Treatment with three infusions of ketamine is acceptable among patients with alcohol use disorder and results in more days of abstinence from alcohol at 6-month follow-up, a study has shown.

Adjunctive ketamine safe, effective in alcohol use disorder

07 Feb 2022

Is coffee protective against AD?

07 Feb 2022 by

Habitual consumption of coffee may be protective against Alzheimer’s disease (AD), suggests a longitudinal study from Australia.

Is coffee protective against AD?

07 Feb 2022

Anxiety during pregnancy speeds up genetic ageing in baby boys

07 Feb 2022 by

Prenatal maternal anxiety is correlated with markers of epigenetic age acceleration in male infants, irrespective of other genetic, socioeconomic, or obstetric risk factors, according to a recent study

Anxiety during pregnancy speeds up genetic ageing in baby boys

07 Feb 2022

Haemostatic powder noninferior to standard treatment for upper GI bleeding

07 Feb 2022 by

TC-325, a bentonite haemostatic powder with aluminium phyllosilicate clay as the main ingredient, is found to be comparable to standard treatment in controlling active upper gastrointestinal bleeding, according to results of a randomized clinical trial by the Chinese University of Hong Kong (CUHK), King Chulalongkorn Memorial University Hospital in Thailand, and Changi General Hospital in Singapore.

Haemostatic powder noninferior to standard treatment for upper GI bleeding

07 Feb 2022

Combining mogamulizumab with nivolumab of no benefit in advanced solid tumours

07 Feb 2022

The addition of mogamulizumab to nivolumab falls short of improving efficacy of the latter in the treatment of patients with locally advanced or metastatic solid tumours, according to the results of a phase I/II trial.

Combining mogamulizumab with nivolumab of no benefit in advanced solid tumours

07 Feb 2022

Efavirenz efficacy not compromised when switched to lower dose

06 Feb 2022

In the management of virologically suppressed patients living with HIV, efavirenz 400 mg has noninferior efficacy and favourable safety as compared with the 600 mg-based regimen, according to a study from China.

Efavirenz efficacy not compromised when switched to lower dose

06 Feb 2022

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Next-gen sequencing paves way to discovery of novel forms of monogenic diabetes

Next-gen sequencing paves way to discovery of novel forms of monogenic diabetes

Adherence to lenalidomide deficient in multiple myeloma patients

Adherence to lenalidomide deficient in multiple myeloma patients

Pandemic interventions help lessen invasive bacterial infections in children

Pandemic interventions help lessen invasive bacterial infections in children

Social unrest and pandemic take a toll on HK women’s mental health

Social unrest and pandemic take a toll on HK women’s mental health

Adjunctive ketamine safe, effective in alcohol use disorder

Adjunctive ketamine safe, effective in alcohol use disorder

Is coffee protective against AD?

Is coffee protective against AD?

Anxiety during pregnancy speeds up genetic ageing in baby boys

Anxiety during pregnancy speeds up genetic ageing in baby boys

Haemostatic powder noninferior to standard treatment for upper GI bleeding

Haemostatic powder noninferior to standard treatment for upper GI bleeding

Combining mogamulizumab with nivolumab of no benefit in advanced solid tumours

Combining mogamulizumab with nivolumab of no benefit in advanced solid tumours

Efavirenz efficacy not compromised when switched to lower dose

Efavirenz efficacy not compromised when switched to lower dose