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TAF rivals TDF for CHB suppression after orthotopic liver transplantation

17 Nov 2021 by

Switching from tenofovir disoproxil fumarate (TDF) regimens to tenofovir alafenamide (TAF) monotherapy demonstrates long-term efficacy and safety in orthotopic liver transplantation (OLT) recipients with chronic hepatitis B virus (HBV) infection, reports a study presented at The Liver Meeting Digital Experience 2021, by the American Association for the Study of Liver Diseases (AASLD 2021).

TAF rivals TDF for CHB suppression after orthotopic liver transplantation

17 Nov 2021

Original New Drug Application Approvals by US FDA (01-15 November 2021)

17 Nov 2021

New drug applications approved by US FDA as of 01-15 November 2021 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (01-15 November 2021)

17 Nov 2021

Insulin hypersecretion, not resistance, tied to arterial stiffness in young adults

17 Nov 2021

Postloading insulinaemia appears to be linked to arterial stiffness in young individuals, a recent Japan study has found. In contrast, insulin sensitivity (SI) shows no such effect.

Insulin hypersecretion, not resistance, tied to arterial stiffness in young adults

17 Nov 2021

Fenfluramine helps minimize day-to-day seizure burden in Dravet syndrome

17 Nov 2021

Treatment with fenfluramine in patients with Dravet syndrome (DS) appears to produce a marked reduction in day-to-day seizure burden and provide prolonged periods of convulsive seizure-free days, as shown in a study.

Fenfluramine helps minimize day-to-day seizure burden in Dravet syndrome

17 Nov 2021

Retinopathy of prematurity outcomes better with anti-VEGF than primary laser treatment

17 Nov 2021

Children with retinopathy of prematurity (ROP) who receive antivascular endothelial growth factor (anti-VEGF) therapy fare better than their counterparts who undergo primary laser treatment, a study has found.

Retinopathy of prematurity outcomes better with anti-VEGF than primary laser treatment

17 Nov 2021

Tobacco control main contributor to Hong Kong’s world-leading longevity

17 Nov 2021 by

A study led by the University of Hong Kong (HKU) has identified stringent tobacco control and resulting low smoking rates as the key reasons behind Hong Kong’s world-leading longevity.

Tobacco control main contributor to Hong Kong’s world-leading longevity

17 Nov 2021

Pacemaker-based cardiac neuromodulation therapy lowers SBP, pulse pressure in patients with ISH

17 Nov 2021 by

Adding BackBeat cardiac neuromodulation therapy™ (Backbeat CNT), a pacemaker-based treatment for hypertension, on top of medical therapy significantly reduces systolic blood pressure (SBP) and pulse pressure, without reducing diastolic blood pressure (DBP), compared with medical therapy alone in patients with isolated systolic hypertension (ISH), according to a study presented at TCT 2021.

Pacemaker-based cardiac neuromodulation therapy lowers SBP, pulse pressure in patients with ISH

17 Nov 2021

Allergy testing during pregnancy could prevent unnecessary antibiotic exposure

16 Nov 2021 by

Women who have a documented history of penicillin allergy should undergo allergy tests during pregnancy to avoid exposure to potentially less effective broad-spectrum antibiotics, according to a small study presented at ACAAI 2021.

Allergy testing during pregnancy could prevent unnecessary antibiotic exposure

16 Nov 2021

High baseline leptin linked to arterial stiffening in men

16 Nov 2021

High levels of circulating leptin may be a risk factor for arterial stiffening and elevated pulse pressure in men, regardless of body weight, a recent study has found.

High baseline leptin linked to arterial stiffening in men

16 Nov 2021

SURTAVI: TAVR matches SAVR through 5 years in intermediate-risk AS patients

16 Nov 2021 by

The noninferiority finding between transcatheter vs surgical aortic valve replacement (TAVR vs SAVR) in intermediate-risk patients with severe aortic stenosis (AS) holds up through 5 years, according to long-term data of the SURTAVI trial presented at TCT 2021, providing reassurance that the less invasive procedure performs just as good in the elderly population.

SURTAVI: TAVR matches SAVR through 5 years in intermediate-risk AS patients

16 Nov 2021

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TAF rivals TDF for CHB suppression after orthotopic liver transplantation

TAF rivals TDF for CHB suppression after orthotopic liver transplantation

Original New Drug Application Approvals by US FDA (01-15 November 2021)

Original New Drug Application Approvals by US FDA (01-15 November 2021)

Insulin hypersecretion, not resistance, tied to arterial stiffness in young adults

Insulin hypersecretion, not resistance, tied to arterial stiffness in young adults

Fenfluramine helps minimize day-to-day seizure burden in Dravet syndrome

Fenfluramine helps minimize day-to-day seizure burden in Dravet syndrome

Retinopathy of prematurity outcomes better with anti-VEGF than primary laser treatment

Retinopathy of prematurity outcomes better with anti-VEGF than primary laser treatment

Tobacco control main contributor to Hong Kong’s world-leading longevity

Tobacco control main contributor to Hong Kong’s world-leading longevity

Pacemaker-based cardiac neuromodulation therapy lowers SBP, pulse pressure in patients with ISH

Pacemaker-based cardiac neuromodulation therapy lowers SBP, pulse pressure in patients with ISH

Allergy testing during pregnancy could prevent unnecessary antibiotic exposure

Allergy testing during pregnancy could prevent unnecessary antibiotic exposure

High baseline leptin linked to arterial stiffening in men

High baseline leptin linked to arterial stiffening in men

SURTAVI: TAVR matches SAVR through 5 years in intermediate-risk AS patients

SURTAVI: TAVR matches SAVR through 5 years in intermediate-risk AS patients