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Familial hypercholesterolemia a risk factor for cerebral small vessel disease

Individuals with familial hypercholesterolemia (FH) appear to be at increased risk of lacunes and cerebral microbleeds, as reported in a study from Japan.

Familial hypercholesterolemia a risk factor for cerebral small vessel disease

20 hours ago

SGLT2 inhibitors lower stroke, mortality risks in AF patients with T2DM

a day ago

Treatment with SGLT2 inhibitors appears to reduce the risks of stroke, dementia, long-standing persistent atrial fibrillation (AF), heart failure, and mortality in patients with both AF and type 2 diabetes mellitus (T2DM), suggests a recent study.

SGLT2 inhibitors lower stroke, mortality risks in AF patients with T2DM

a day ago

7,000 steps a day may be enough

29 Aug 2025 by

Walking 7,000 steps a day can offer the same health benefits as walking 10,000 steps a day, according to a comprehensive review and meta-analysis. Experts said it could be a more realistic target than the 10,000 steps, which is traditionally seen as the benchmark to reach.

7,000 steps a day may be enough

29 Aug 2025

Does hyperaldosteronism drive increased salt-sensitive BP in women?

28 Aug 2025 by

Salt-sensitive blood pressure (SSBP), aldosterone response to angiotensin II, and aldosterone/plasma renin activity (PRA) ratios are all greater in women than in men, suggests a study. However, men show higher levels of basal aldosterone and its secretagogues.

Does hyperaldosteronism drive increased salt-sensitive BP in women?

28 Aug 2025

Exercise plus diet reduces weight, but does little to improve hip pain

28 Aug 2025

The addition of a weight-loss diet to exercise does not appear to change hip pain severity, in adults with hip osteoarthritis and overweight or obesity. However, it results in improvements in most other outcomes such as body weight and body composition.

Exercise plus diet reduces weight, but does little to improve hip pain

28 Aug 2025

Canagliflozin lowers HbA1c levels in children with T2DM

27 Aug 2025

Treatment with canagliflozin significantly reduces haemoglobin A1c (HbA1c) in children and adolescents with type 2 diabetes mellitus (T2DM), with a safety profile comparable to that seen in adults, results of a phase III trial have shown.

Canagliflozin lowers HbA1c levels in children with T2DM

27 Aug 2025

TyG index linked to hypertension incidence

27 Aug 2025

The triglyceride-glucose (TyG) index can be used to predict the incidence of hypertension, according to a study involving a population-based sample of Japanese men.

TyG index linked to hypertension incidence

27 Aug 2025

Age at menarche may signal health risks

26 Aug 2025 by

Findings from The Brazilian Longitudinal Study of Adult Health (ELSA-Brazil) presented at ENDO 2025 demonstrate an association between early and late age at menarche and distinct cardiometabolic and reproductive health risks.

Age at menarche may signal health risks

26 Aug 2025

Dalpiciclib-pyrotinib-endocrine therapy passes trial for breast cancer

25 Aug 2025 by

Treatment with dalpiciclib combined with pyrotinib and endocrine therapy exhibits antitumour activity with no new safety signals in estrogen receptor (ER)-positive HER2-positive advanced breast cancer, as shown by the results of a phase II trial.

Dalpiciclib-pyrotinib-endocrine therapy passes trial for breast cancer

25 Aug 2025

Metformin use in pregnancy brings benefits to mums but also more risks to babies

24 Aug 2025 by

In pregnant women with polycystic ovary syndrome (PCOS), treatment with metformin appears to protect against infections throughout pregnancy while also contributing to an increased risk of childhood allergies and eczema in the offspring, according to post hoc analyses of two randomized controlled trials and one related follow-up study.

Metformin use in pregnancy brings benefits to mums but also more risks to babies

24 Aug 2025

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Familial hypercholesterolemia a risk factor for cerebral small vessel disease

Familial hypercholesterolemia a risk factor for cerebral small vessel disease

SGLT2 inhibitors lower stroke, mortality risks in AF patients with T2DM

SGLT2 inhibitors lower stroke, mortality risks in AF patients with T2DM

7,000 steps a day may be enough

7,000 steps a day may be enough

Does hyperaldosteronism drive increased salt-sensitive BP in women?

Does hyperaldosteronism drive increased salt-sensitive BP in women?

Exercise plus diet reduces weight, but does little to improve hip pain

Exercise plus diet reduces weight, but does little to improve hip pain

Canagliflozin lowers HbA1c levels in children with T2DM

Canagliflozin lowers HbA1c levels in children with T2DM

TyG index linked to hypertension incidence

TyG index linked to hypertension incidence

Age at menarche may signal health risks

Age at menarche may signal health risks

Dalpiciclib-pyrotinib-endocrine therapy passes trial for breast cancer

Dalpiciclib-pyrotinib-endocrine therapy passes trial for breast cancer

Metformin use in pregnancy brings benefits to mums but also more risks to babies

Metformin use in pregnancy brings benefits to mums but also more risks to babies