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Study: Avoid early 5-ASA treatment, adopt biologic-first approach in paediatric CD

Early treatment with 5-aminosalicylates (5-ASA) holds little benefit in children with newly diagnosed Crohn’s disease (CD), being associated with higher treatment failure rates, increased corticosteroid use, and reduced subsequent biologic therapy durability, according to a study.

Study: Avoid early 5-ASA treatment, adopt biologic-first approach in paediatric CD

a day ago

Novel glucagon/GLP-1 receptor dual agonist helps reduce liver fat

17 Sep 2026

In patients with metabolic dysfunction-associated steatotic liver disease or steatohepatitis, treatment with the novel glucagon and GLP-1 receptor dual agonist DD01 is associated with rapid reductions in liver fat, according to a phase II study.

Novel glucagon/GLP-1 receptor dual agonist helps reduce liver fat

17 Sep 2026

Multistrain probiotics may protect against necrotizing enterocolitis

16 Sep 2026 by

Routine supplementation with a multistrain probiotic appears to lead to a reduction in the incidence of necrotizing enterocolitis (NEC) in preterm infants, as shown in a Dutch implementation study.

Multistrain probiotics may protect against necrotizing enterocolitis

16 Sep 2026

Vegan diet shrinks skeletal muscle mass in older adults, but resistance exercise helps

16 Sep 2026 by

A self-selected vegan diet may compromise protein intake, skeletal muscle mass, and muscle protein synthesis (MPS) in healthy, older adults, suggests a study. However, resistance exercise (RE) may mitigate the negative effects of this diet on skeletal muscle.

Vegan diet shrinks skeletal muscle mass in older adults, but resistance exercise helps

16 Sep 2026

Early life sugar restriction tied to lower risk of early-onset cancer

16 Sep 2026

Limiting the intake of sugar during the first 1,000 days of life may help prevent early-onset cancer and extend disease-free lifespan, suggests a study.

Early life sugar restriction tied to lower risk of early-onset cancer

16 Sep 2026

Novel anal plug may help control faecal incontinence

15 Sep 2026 by

A single-use anal insert device appears to be a safe and effective option for patients with faecal incontinence (FI) refractory to medical and behavioural therapy, having been shown to reduce the frequency of episodes in a trial.

Novel anal plug may help control faecal incontinence

15 Sep 2026

French study highlights atezolizumab–bevacizumab benefit in HCC

08 Sep 2026 by

Four-year updates from the CHIEF study show a durable survival benefit with atezolizumab plus bevacizumab in individuals with advanced hepatocellular carcinoma (HCC).

French study highlights atezolizumab–bevacizumab benefit in HCC

08 Sep 2026

Resistant starch supplementation helps improve metabolic, gut health

07 Sep 2026

A narrative review suggests the potential of resistant starch (RS) as a dietary strategy for supporting metabolic and gut health in Asia-Pacific populations undergoing rapid nutritional transition.