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Schizophrenia: Clozapine a better fit for second relapse prevention
A population-based cohort study in Finland has revealed that clozapine initiation after a first-episode schizophrenia relapse is associated with a lower risk of second relapse compared with continuation with the same antipsychotic or switching to another non-clozapine oral antipsychotic. These findings challenge current guidelines that recommend clozapine as a third-line treatment.
Schizophrenia: Clozapine a better fit for second relapse prevention
06 Feb 2025
Combination therapy slows cognitive decline in depression and MCI
Cognitive remediation (CR) plus transcranial direct current stimulation (tDCS) is effective in slowing cognitive decline in older adults with remitted major depressive disorder (MDD), mild cognitive impairment (MCI), or both, according to a randomized clinical trial.
Combination therapy slows cognitive decline in depression and MCI
06 Feb 2025
Pandemic babies have a 46 percent higher risk of atopic diseases
The incidence of atopic diseases in infants born in Hong Kong has increased by 46 percent during the COVID-19 pandemic, potentially linked to altered neonatal microbiome diversity resulting from vigorous disinfection. SIM03 and SIM05, symbiotic formulae developed with the aid of artificial intelligence (AI), are shown to improve eczema severity and quality of life (QoL) in children and adults, respectively, by modulating gut microbiota.
