News &amp; Updates

For a carefully selected group of patients with medically refractory, lung-limited, stage IV non-small cell lung cancer (NSCLC), bilateral lung transplant appears beneficial, being associated with favourable early survival outcomes, as shown in a study.

Lung transplant shows signal of benefit in select lung cancer patients

Higher medial-to-lateral sBMD tied to OA knee pain presence, progression

A higher ratio of medial-to-lateral subchondral bone mineral density (sBMD) appears predictive of the presence and progression of knee pain in people with osteoarthritis (OA), suggests a study.

Higher medial-to-lateral sBMD tied to OA knee pain presence, progression

Early-onset RIL in glioblastoma patients treated with STUPP warrants monitoring

Nearly a third of glioblastoma patients treated with standard radiotherapy plus temozolomide (STUPP protocol) suffer early-onset radiation induced leukoencephalopathy (RIL), which is linked to early cognitive and functional decline, according to a study.

Early-onset RIL in glioblastoma patients treated with STUPP warrants monitoring

Novel BTK inhibitor on par with ocrelizumab in reducing disability progression in PPMS

The investigational Bruton’s tyrosine kinase (BTK) inhibitor fenebrutinib demonstrates its noninferiority to ocrelizumab in reducing the risk of disability progression in patients with primary progressive multiple sclerosis (PPMS) in the phase III FENtrepid study.

Novel BTK inhibitor on par with ocrelizumab in reducing disability progression in PPMS

17 Jul 2026

Does MS relapse after stopping ponesimod?

In a post hoc analysis of the OPTIMUM* long-term extension (OPTIMUM-LTE) study, discontinuation of ponesimod did not lead to a clinically meaningful disease reactivation or rebound effect in patients with relapsing multiple sclerosis (MS).

Does MS relapse after stopping ponesimod?

Prenatal paracetamol exposure cleared of ASD, ADHD risk in offspring

Children born to mothers who used paracetamol during pregnancy are unlikely to develop autism spectrum disorder (ASD) or attention-deficit/hyperactivity disorder (ADHD), according to a study from Hong Kong.

Prenatal paracetamol exposure cleared of ASD, ADHD risk in offspring

Nanoencapsulated sirolimus plus pegadricase helps patients with uncontrolled gout

Treatment with nanoencapsulated sirolimus plus pegadricase yields higher response rates compared with placebo in patients with uncontrolled gout, according to the phase III DISSOLVE I and II studies.

Nanoencapsulated sirolimus plus pegadricase helps patients with uncontrolled gout

Elobixibat bests prucalopride for functional constipation in head-to-head trial

16 Jul 2026 by

Elobixibat delivers superior symptom relief and quality-of-life improvements compared with prucalopride in the second-line treatment of patients with functional constipation, as shown in a head-to-head trial.

Elobixibat bests prucalopride for functional constipation in head-to-head trial

Medication nonadherence more common in young vs older adults with SLE

Self-reported medication nonadherence is greater among younger vs older adults with systemic lupus erythematosus (SLE), driven primarily by logistical barriers, reports a study.

Medication nonadherence more common in young vs older adults with SLE