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SHASTA trials boost plozasiran potential in severe hypertriglyceridaemia
10 Sep 2026
byAudrey Abella
In the SHASTA-3 and SHASTA-4 trials, quarterly administration of plozasiran reduced triglyceride (TG) levels and acute pancreatitis (AP) events in individuals with severe hypertriglyceridaemia (sHTG; TG ≥500 mg/dL).
SHASTA trials boost plozasiran potential in severe hypertriglyceridaemia
10 Sep 2026
Tailored therapy reduces antibiotic use in infective endocarditis
09 Sep 2026
byStephen Padilla
A response-tailored strategy decreases antibiotic duration by 2 weeks compared with standard therapy in patients with left-sided infective endocarditis, without compromising their safety. This is the primary result of the POET-II study presented at ESC Congress 2026.







