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Dual-target vaccine for flu, COVID-19 compares favourably with standalone comparators

18 Jun 2025 by

The investigational influenza–COVID-19 combination vaccine mRNA-1083 has demonstrated noninferiority to recommended standard-care flu and COVID-19 vaccines, with higher immune responses and an acceptable safety profile in adults at least 50 years of age, according to the results of a phase III trial.

Dual-target vaccine for flu, COVID-19 compares favourably with standalone comparators

18 Jun 2025

First-line methotrexate on par with prednisone for sarcoidosis

18 Jun 2025 by

The use of methotrexate as a first line of treatment for patients with pulmonary sarcoidosis delivers similar efficacy to prednisone as measured by forced vital capacity after 24 weeks, results of the PREDMETH trial have shown.

First-line methotrexate on par with prednisone for sarcoidosis

18 Jun 2025

Digital therapy improves life quality of patients with pulmonary fibrosis

18 Jun 2025 by

A novel digital psychological therapy, named Almee, demonstrates efficacy in improving health-related quality of life (HRQOL) in patients with pulmonary fibrosis, irrespective of antifibrotic treatment use, reports a study presented at ATS 2025.

Digital therapy improves life quality of patients with pulmonary fibrosis

18 Jun 2025

Inclisiran superior to ezetimibe in LDL-C reduction in patients without ASCVD

18 Jun 2025

Treatment with inclisiran monotherapy demonstrates good tolerability and better reduction in low-density lipoprotein cholesterol (LDL-C) levels when compared with ezetimibe and placebo in patients without atherosclerotic cardiovascular disease (ASCVD), reports a study.

Inclisiran superior to ezetimibe in LDL-C reduction in patients without ASCVD

18 Jun 2025

RSV-ARI nearly triples mortality risk in new study

18 Jun 2025 by

Acute respiratory infection caused by respiratory syncytial virus (RSV-ARI) nearly triples the risk of death, particularly among individuals with chronic underlying respiratory conditions, as shown in a nationwide cohort study in Denmark.

RSV-ARI nearly triples mortality risk in new study

18 Jun 2025

Coil plus glue therapy beneficial for gastric varices

18 Jun 2025 by

Cyanoacrylate (CYA) injection delivers better results when augmented with endoscopic ultrasonography (EUS)-guided coil embolization for gastric variceal obliteration in a single-centre study.

Coil plus glue therapy beneficial for gastric varices

18 Jun 2025

Adalimumab delivers consistent benefit in plaque psoriasis, with or without methotrexate

18 Jun 2025

Treatment outcomes with adalimumab for plaque psoriasis appear to be similar between patients on monotherapy and those receiving concomitant methotrexate, according to the BSTOP study.

Adalimumab delivers consistent benefit in plaque psoriasis, with or without methotrexate

18 Jun 2025

Ferric carboxymaltose infusion offers little help in iron-deficient patients with heart failure

17 Jun 2025

Intravenous ferric carboxymaltose does not appear to be beneficial in terms of heart failure (HF) hospitalization and cardiovascular mortality in patients with HF and iron deficiency, according to a study.

Ferric carboxymaltose infusion offers little help in iron-deficient patients with heart failure

17 Jun 2025

Glucose-lowering med shows promise for treating kidney stones in nondiabetics

17 Jun 2025 by

Treatment with the sodium-glucose cotransporter 2 (SGLT2) inhibitor empagliflozin helps improve the urinary lithogenic risk profile of nondiabetic patients with calcium and uric acid stones, as shown in the results of the randomized crossover SWEETSTONE trial.

Glucose-lowering med shows promise for treating kidney stones in nondiabetics

17 Jun 2025

Childhood adversity may lead to adult obesity

17 Jun 2025 by

Adverse childhood experiences (ACEs), such as abuse, neglect, and household dysfunction, appear to contribute to the development of obesity during adulthood, suggests an Iraq study presented at ESPGHAN 2025.

Childhood adversity may lead to adult obesity

17 Jun 2025

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Dual-target vaccine for flu, COVID-19 compares favourably with standalone comparators

Dual-target vaccine for flu, COVID-19 compares favourably with standalone comparators

First-line methotrexate on par with prednisone for sarcoidosis

First-line methotrexate on par with prednisone for sarcoidosis

Digital therapy improves life quality of patients with pulmonary fibrosis

Digital therapy improves life quality of patients with pulmonary fibrosis

Inclisiran superior to ezetimibe in LDL-C reduction in patients without ASCVD

Inclisiran superior to ezetimibe in LDL-C reduction in patients without ASCVD

RSV-ARI nearly triples mortality risk in new study

RSV-ARI nearly triples mortality risk in new study

Coil plus glue therapy beneficial for gastric varices

Coil plus glue therapy beneficial for gastric varices

Adalimumab delivers consistent benefit in plaque psoriasis, with or without methotrexate

Adalimumab delivers consistent benefit in plaque psoriasis, with or without methotrexate

Ferric carboxymaltose infusion offers little help in iron-deficient patients with heart failure

Ferric carboxymaltose infusion offers little help in iron-deficient patients with heart failure

Glucose-lowering med shows promise for treating kidney stones in nondiabetics

Glucose-lowering med shows promise for treating kidney stones in nondiabetics

Childhood adversity may lead to adult obesity

Childhood adversity may lead to adult obesity